Reshaping the binding channel of a novel GH113 family β-mannanase from Paenibacillus cineris (PcMan113) for enhanced activity

Reshaping the binding channel of a novel GH113 family β-mannanase from Paenibacillus cineris (PcMan113) for enhanced activity

Abstract Endo-β-mannanases are important enzymes for degrading lignocellulosic biomass to generate mannan, which has significant health effects as a prebiotic that promotes the development of gut microbiota. Here, a novel endo-β-mannanase belonging to glycoside hydrolase (GH) family 113 from Paeniba...

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Bibliographic Details
Main Authors: Dengyue Sun, Chao Li, Pengpeng Cui, Jie Zhang, Yaolin Zhou, Mian Wu, Xia Li, Teng-fei Wang, Zhixiong Zeng, Hui-Min Qin
Format: Article
Language:English
Published: SpringerOpen 2022-03-01
Series:Bioresources and Bioprocessing
Subjects:
Endo-β-mannanase
GH113 family
Structural analysis
Binding channel
Molecular dynamics
Online Access:https://doi.org/10.1186/s40643-022-00505-7

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