Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment

The last decades have brought impressive advances in liver transplantation. As a result, there was a notable rise in the number of liver transplants globally. Advances in surgical techniques, immunosuppressive therapies and radiologically guided treatments have led to an improvement in the prognosis...

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Main Authors: Gina Gheorghe, Camelia Cristina Diaconu, Simona Bungau, Nicolae Bacalbasa, Natalia Motas, Vlad-Alexandru Ionescu
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/5/850
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author Gina Gheorghe
Camelia Cristina Diaconu
Simona Bungau
Nicolae Bacalbasa
Natalia Motas
Vlad-Alexandru Ionescu
author_facet Gina Gheorghe
Camelia Cristina Diaconu
Simona Bungau
Nicolae Bacalbasa
Natalia Motas
Vlad-Alexandru Ionescu
author_sort Gina Gheorghe
collection DOAJ
description The last decades have brought impressive advances in liver transplantation. As a result, there was a notable rise in the number of liver transplants globally. Advances in surgical techniques, immunosuppressive therapies and radiologically guided treatments have led to an improvement in the prognosis of these patients. However, the risk of complications remains significant, and the management of liver transplant patients requires multidisciplinary teams. The most frequent and severe complications are biliary and vascular complications. Compared to vascular complications, biliary complications have higher incidence rates but a better prognosis. The early diagnosis and selection of the optimal treatment are crucial to avoid the loss of the graft and even the death of the patient. The development of minimally invasive techniques prevents surgical reinterventions with their associated risks. Liver retransplantation remains the last therapeutic solution for graft dysfunction, one of the main problems, in this case, being the low number of donors.
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spelling doaj.art-e073f8b1a5174c32b18ccd64782f5ba72023-11-18T02:21:09ZengMDPI AGMedicina1010-660X1648-91442023-04-0159585010.3390/medicina59050850Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to TreatmentGina Gheorghe0Camelia Cristina Diaconu1Simona Bungau2Nicolae Bacalbasa3Natalia Motas4Vlad-Alexandru Ionescu5Faculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, RomaniaDepartment of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, RomaniaFaculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, RomaniaInstitute of Oncology “Profesor Doctor Alexandru Trestioreanu” Bucharest, 022328 Bucharest, RomaniaFaculty of Medicine, University of Medicine and Pharmacy Carol Davila Bucharest, 050474 Bucharest, RomaniaThe last decades have brought impressive advances in liver transplantation. As a result, there was a notable rise in the number of liver transplants globally. Advances in surgical techniques, immunosuppressive therapies and radiologically guided treatments have led to an improvement in the prognosis of these patients. However, the risk of complications remains significant, and the management of liver transplant patients requires multidisciplinary teams. The most frequent and severe complications are biliary and vascular complications. Compared to vascular complications, biliary complications have higher incidence rates but a better prognosis. The early diagnosis and selection of the optimal treatment are crucial to avoid the loss of the graft and even the death of the patient. The development of minimally invasive techniques prevents surgical reinterventions with their associated risks. Liver retransplantation remains the last therapeutic solution for graft dysfunction, one of the main problems, in this case, being the low number of donors.https://www.mdpi.com/1648-9144/59/5/850liver transplantationbiliary complicationsvascular complicationsgraft dysfunction
spellingShingle Gina Gheorghe
Camelia Cristina Diaconu
Simona Bungau
Nicolae Bacalbasa
Natalia Motas
Vlad-Alexandru Ionescu
Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
Medicina
liver transplantation
biliary complications
vascular complications
graft dysfunction
title Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
title_full Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
title_fullStr Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
title_full_unstemmed Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
title_short Biliary and Vascular Complications after Liver Transplantation–From Diagnosis to Treatment
title_sort biliary and vascular complications after liver transplantation from diagnosis to treatment
topic liver transplantation
biliary complications
vascular complications
graft dysfunction
url https://www.mdpi.com/1648-9144/59/5/850
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AT cameliacristinadiaconu biliaryandvascularcomplicationsafterlivertransplantationfromdiagnosistotreatment
AT simonabungau biliaryandvascularcomplicationsafterlivertransplantationfromdiagnosistotreatment
AT nicolaebacalbasa biliaryandvascularcomplicationsafterlivertransplantationfromdiagnosistotreatment
AT nataliamotas biliaryandvascularcomplicationsafterlivertransplantationfromdiagnosistotreatment
AT vladalexandruionescu biliaryandvascularcomplicationsafterlivertransplantationfromdiagnosistotreatment