A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.

Bibliographic Details
Main Authors: Arturo San Feliciano, Manuel Medarde, Concepción P. Melero
Format: Article
Language:English
Published: MDPI AG 2000-01-01
Series:Molecules
Subjects:
Digitalis glycosides analogues
structure-activity relationships
inotropic activity
Na+
K+-ATPase
aminoguanidine analogues
Online Access:http://www.mdpi.com/1420-3049/5/1/51/
Description
Summary:A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.
ISSN:1420-3049

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