A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues

A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.

Bibliographic Details
Main Authors: Arturo San Feliciano, Manuel Medarde, Concepción P. Melero
Format: Article
Language:English
Published: MDPI AG 2000-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/5/1/51/
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author Arturo San Feliciano
Manuel Medarde
Concepción P. Melero
author_facet Arturo San Feliciano
Manuel Medarde
Concepción P. Melero
author_sort Arturo San Feliciano
collection DOAJ
description A short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.
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spelling doaj.art-e0747618590d406fbb3500e08f74aa832022-12-21T18:42:58ZengMDPI AGMolecules1420-30492000-01-0151518110.3390/50100051A Short Review on Cardiotonic Steroids and Their Aminoguanidine AnaloguesArturo San FelicianoManuel MedardeConcepción P. MeleroA short review on cardiotonic steroids and their analogues is presented. The natural, semisynthetic and synthetic derivatives, as well as their mechanism of action and structure-activity relationships are shown, with a special reference to aminoguanidine derivatives.http://www.mdpi.com/1420-3049/5/1/51/Digitalis glycosides analoguesstructure-activity relationshipsinotropic activityNa+K+-ATPaseaminoguanidine analogues
spellingShingle Arturo San Feliciano
Manuel Medarde
Concepción P. Melero
A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
Molecules
Digitalis glycosides analogues
structure-activity relationships
inotropic activity
Na+
K+-ATPase
aminoguanidine analogues
title A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
title_full A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
title_fullStr A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
title_full_unstemmed A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
title_short A Short Review on Cardiotonic Steroids and Their Aminoguanidine Analogues
title_sort short review on cardiotonic steroids and their aminoguanidine analogues
topic Digitalis glycosides analogues
structure-activity relationships
inotropic activity
Na+
K+-ATPase
aminoguanidine analogues
url http://www.mdpi.com/1420-3049/5/1/51/
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