Anthelmintic acetogenin from Annona squamosa L. Seeds
Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined a...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Ciências
2008-06-01
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| Series: | Anais da Academia Brasileira de Ciências |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000200005 |
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| author | Marta M.C. Souza Claudia M.L. Bevilaqua Selene M. Morais Cícero T.C. Costa Ana R.A. Silva Raimundo Braz-Filho |
| author_facet | Marta M.C. Souza Claudia M.L. Bevilaqua Selene M. Morais Cícero T.C. Costa Ana R.A. Silva Raimundo Braz-Filho |
| author_sort | Marta M.C. Souza |
| collection | DOAJ |
| description | Annona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis.<br>Extratos das sementes de Annona squamosa demonstraram atividade anti-helmíntica contra Haemonchus contortus, o principal nematódeo de ovinos e caprinos no Nordeste do Brasil. O composto 1 foi isolado do extrato acetato de etila e inibiu a eclosão dos ovos de H. contortus a 25 mg ml-1. A estrutura de 1 foi determinada como uma acetogenina C37 tri-hidroxi bis-tetrahydrofurano adjacente, baseando-se nos dados espectrais. |
| first_indexed | 2024-12-13T22:18:42Z |
| format | Article |
| id | doaj.art-e07496b0ee8845c2b1d8dd6dd9d2bde8 |
| institution | Directory Open Access Journal |
| issn | 0001-3765 1678-2690 |
| language | English |
| last_indexed | 2024-12-13T22:18:42Z |
| publishDate | 2008-06-01 |
| publisher | Academia Brasileira de Ciências |
| record_format | Article |
| series | Anais da Academia Brasileira de Ciências |
| spelling | doaj.art-e07496b0ee8845c2b1d8dd6dd9d2bde82022-12-21T23:29:27ZengAcademia Brasileira de CiênciasAnais da Academia Brasileira de Ciências0001-37651678-26902008-06-0180227127710.1590/S0001-37652008000200005Anthelmintic acetogenin from Annona squamosa L. SeedsMarta M.C. SouzaClaudia M.L. BevilaquaSelene M. MoraisCícero T.C. CostaAna R.A. SilvaRaimundo Braz-FilhoAnnona squamosa seeds extracts showed anthelmintic activity against Haemonchus contortus, the main nematode of sheep and goat in Northeastern Brazil. A compound 1 was isolated from ethyl acetate extract and inhibited the egg hatching of H. contortus at 25 mg ml-1. The structure of 1 was determined as a C37 trihydroxy adjacent bistetrahydrofuran acetogenin based on spectroscopic analysis.<br>Extratos das sementes de Annona squamosa demonstraram atividade anti-helmíntica contra Haemonchus contortus, o principal nematódeo de ovinos e caprinos no Nordeste do Brasil. O composto 1 foi isolado do extrato acetato de etila e inibiu a eclosão dos ovos de H. contortus a 25 mg ml-1. A estrutura de 1 foi determinada como uma acetogenina C37 tri-hidroxi bis-tetrahydrofurano adjacente, baseando-se nos dados espectrais.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000200005Haemonchus contortusnematódeosanonáceafitoterapiaHaemonchus contortusnematodesAnnonaceaphytotherapy |
| spellingShingle | Marta M.C. Souza Claudia M.L. Bevilaqua Selene M. Morais Cícero T.C. Costa Ana R.A. Silva Raimundo Braz-Filho Anthelmintic acetogenin from Annona squamosa L. Seeds Anais da Academia Brasileira de Ciências Haemonchus contortus nematódeos anonácea fitoterapia Haemonchus contortus nematodes Annonacea phytotherapy |
| title | Anthelmintic acetogenin from Annona squamosa L. Seeds |
| title_full | Anthelmintic acetogenin from Annona squamosa L. Seeds |
| title_fullStr | Anthelmintic acetogenin from Annona squamosa L. Seeds |
| title_full_unstemmed | Anthelmintic acetogenin from Annona squamosa L. Seeds |
| title_short | Anthelmintic acetogenin from Annona squamosa L. Seeds |
| title_sort | anthelmintic acetogenin from annona squamosa l seeds |
| topic | Haemonchus contortus nematódeos anonácea fitoterapia Haemonchus contortus nematodes Annonacea phytotherapy |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000200005 |
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