DNA assembly for nanopore data storage readout

A major bottleneck in using DNA as a data storage medium is the slowness of sequencing. Here the authors decode 1.67 megabytes of information using a portable nanopore platform with an assembly strategy for increased throughput.

Bibliographic Details
Main Authors: Randolph Lopez, Yuan-Jyue Chen, Siena Dumas Ang, Sergey Yekhanin, Konstantin Makarychev, Miklos Z Racz, Georg Seelig, Karin Strauss, Luis Ceze
Format: Article
Language:English
Published: Nature Portfolio 2019-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-10978-4
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author Randolph Lopez
Yuan-Jyue Chen
Siena Dumas Ang
Sergey Yekhanin
Konstantin Makarychev
Miklos Z Racz
Georg Seelig
Karin Strauss
Luis Ceze
author_facet Randolph Lopez
Yuan-Jyue Chen
Siena Dumas Ang
Sergey Yekhanin
Konstantin Makarychev
Miklos Z Racz
Georg Seelig
Karin Strauss
Luis Ceze
author_sort Randolph Lopez
collection DOAJ
description A major bottleneck in using DNA as a data storage medium is the slowness of sequencing. Here the authors decode 1.67 megabytes of information using a portable nanopore platform with an assembly strategy for increased throughput.
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spelling doaj.art-e07599e4d5704cedbc045adf5c88720f2022-12-21T19:31:56ZengNature PortfolioNature Communications2041-17232019-07-011011910.1038/s41467-019-10978-4DNA assembly for nanopore data storage readoutRandolph Lopez0Yuan-Jyue Chen1Siena Dumas Ang2Sergey Yekhanin3Konstantin Makarychev4Miklos Z Racz5Georg Seelig6Karin Strauss7Luis Ceze8Department of Bioengineering, University of WashingtonMicrosoft ResearchMicrosoft ResearchMicrosoft ResearchMicrosoft ResearchMicrosoft ResearchMolecular Engineering & Sciences Institute, University of WashingtonMicrosoft ResearchPaul G. Allen School for Computer Science & Engineering, University of WashingtonA major bottleneck in using DNA as a data storage medium is the slowness of sequencing. Here the authors decode 1.67 megabytes of information using a portable nanopore platform with an assembly strategy for increased throughput.https://doi.org/10.1038/s41467-019-10978-4
spellingShingle Randolph Lopez
Yuan-Jyue Chen
Siena Dumas Ang
Sergey Yekhanin
Konstantin Makarychev
Miklos Z Racz
Georg Seelig
Karin Strauss
Luis Ceze
DNA assembly for nanopore data storage readout
Nature Communications
title DNA assembly for nanopore data storage readout
title_full DNA assembly for nanopore data storage readout
title_fullStr DNA assembly for nanopore data storage readout
title_full_unstemmed DNA assembly for nanopore data storage readout
title_short DNA assembly for nanopore data storage readout
title_sort dna assembly for nanopore data storage readout
url https://doi.org/10.1038/s41467-019-10978-4
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