The role of cellular senescence in metabolic diseases and the potential for senotherapeutic interventions

The role of cellular senescence in metabolic diseases and the potential for senotherapeutic interventions

Cellular senescence represents an irreversible state of cell cycle arrest induced by various stimuli strongly associated with aging and several chronic ailments. In recent years, studies have increasingly suggested that the accumulation of senescent cells is an important contributor to the decline o...

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Bibliographic Details
Main Authors: Huantong Zhang, Han Zhou, Xin Shen, Xingchen Lin, Yuke Zhang, Yiyi Sun, Yi Zhou, Lei Zhang, Dayong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cellular senescence
metabolic disease
diabetes mellitus
SASP
senolytic
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1276707/full

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