Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study)
Objective: to examine gender-related differences in the postresuscitative brain functional and structural changes.Materials and methods. Congenital and acquired behaviors were studied in 100 adult albino rats of both sexes in the control and after experienced 12-min cardiac arrest during 3 months (6...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2007-12-01
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| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/891 |
| _version_ | 1826562389406908416 |
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| author | A. V. Volkov M. Sh. Avrushchenko N. A. Gorenkova L. N. Shcherbakova Yu. V. Zarzhetsky |
| author_facet | A. V. Volkov M. Sh. Avrushchenko N. A. Gorenkova L. N. Shcherbakova Yu. V. Zarzhetsky |
| author_sort | A. V. Volkov |
| collection | DOAJ |
| description | Objective: to examine gender-related differences in the postresuscitative brain functional and structural changes.Materials and methods. Congenital and acquired behaviors were studied in 100 adult albino rats of both sexes in the control and after experienced 12-min cardiac arrest during 3 months (6 tests); the conditions of highly sensitive to ischemia of cerebral formations were subject to neuromorphological quantitative studies, and biochemical plasma parameters were determined.Results. Sexual differences in the integrative activity of the brain, in the state of neuronal populations in different regions of the hippocampus and cerebellum, and in plasma biochemical parameters were established in normalcy. Common and gender-related functional and structural changes of the brain and changes in plasma biochemical parameters were revealed in the postresuscitative period.Conclusion. Further studies of the gender-related mechanisms of development are required to develop specific methods for the prevention and therapy for disease. |
| first_indexed | 2024-04-10T01:30:57Z |
| format | Article |
| id | doaj.art-e07a6167ed464492bec1fddd3c5450c8 |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2025-03-14T09:47:18Z |
| publishDate | 2007-12-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-e07a6167ed464492bec1fddd3c5450c82025-03-02T11:29:27ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102007-12-01369710210.15360/1813-9779-2007-6-97-102891Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study)A. V. Volkov0M. Sh. Avrushchenko1N. A. Gorenkova2L. N. Shcherbakova3Yu. V. Zarzhetsky4Research Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, MoscowObjective: to examine gender-related differences in the postresuscitative brain functional and structural changes.Materials and methods. Congenital and acquired behaviors were studied in 100 adult albino rats of both sexes in the control and after experienced 12-min cardiac arrest during 3 months (6 tests); the conditions of highly sensitive to ischemia of cerebral formations were subject to neuromorphological quantitative studies, and biochemical plasma parameters were determined.Results. Sexual differences in the integrative activity of the brain, in the state of neuronal populations in different regions of the hippocampus and cerebellum, and in plasma biochemical parameters were established in normalcy. Common and gender-related functional and structural changes of the brain and changes in plasma biochemical parameters were revealed in the postresuscitative period.Conclusion. Further studies of the gender-related mechanisms of development are required to develop specific methods for the prevention and therapy for disease.https://www.reanimatology.com/rmt/article/view/891clinical deathemotional reactivityorientative-exploratory reactionlearningneuronal populationsmorphometric analysisblood biochemistry |
| spellingShingle | A. V. Volkov M. Sh. Avrushchenko N. A. Gorenkova L. N. Shcherbakova Yu. V. Zarzhetsky Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) Общая реаниматология clinical death emotional reactivity orientative-exploratory reaction learning neuronal populations morphometric analysis blood biochemistry |
| title | Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) |
| title_full | Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) |
| title_fullStr | Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) |
| title_full_unstemmed | Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) |
| title_short | Sexual Differences in Delayed Postresuscitative Brain Changes (Experimental Study) |
| title_sort | sexual differences in delayed postresuscitative brain changes experimental study |
| topic | clinical death emotional reactivity orientative-exploratory reaction learning neuronal populations morphometric analysis blood biochemistry |
| url | https://www.reanimatology.com/rmt/article/view/891 |
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