Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH

Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH

Cellular senescence is a state of irreversible cell cycle arrest and has been shown to play a key role in many diseases, including metabolic diseases. To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derangements associated with non-alcoholic steatohepatit...

Full description

Bibliographic Details
Main Authors: Laurianne Bonnet, Ida Alexandersson, Ritesh K. Baboota, Tobias Kroon, Jan Oscarsson, Ulf Smith, Jeremie Boucher
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Endocrinology
Subjects:
senescence
NAFLD
NASH
hepatocytes
insulin signaling
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.957616/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.957616/full

Similar Items