PKCδ promotes the invasion and migration of colorectal cancer through c-myc/NDRG1 pathway

PKCδ promotes the invasion and migration of colorectal cancer through c-myc/NDRG1 pathway

ObjectiveColorectal cancer (CRC) is the third cause of expected cancer deaths both in men and women in the U.S. and the third most commonly diagnosed cancer in China Targeted therapy has been proven to improve overall survival for unresectable metastatic CRC. But the location of the primary tumor or...

Full description

Bibliographic Details
Main Authors:	Hong-tao Jia, Yan-fei Shao, Xue-liang Zhou, Guang Yang, Ling Huang, Batuer Aikemu, Shu-chun Li, Cheng-sheng Ding, Xiao-dong Fan, Hi-ju Hong, Sen Zhang, Rui-jun Pan, Jing Sun
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Series:	Frontiers in Oncology
Subjects:	colorectal cancer protein kinase C δ N-myc downstream-regulated gene 1 metastasis epithelial-mesenchymal transition
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1026561/full

Similar Items

ACACB is a novel metabolism-related biomarker in the prediction of response to cetuximab therapy inmetastatic colorectal cancer
by: Hong Hi-Ju, et al.
Published: (2022-09-01)

An Original Ferroptosis-Related Gene Signature Effectively Predicts the Prognosis and Clinical Status for Colorectal Cancer Patients
by: Yanfei Shao, et al.
Published: (2021-06-01)

Comprehensive exploration of tumor immune microenvironment feature and therapeutic response in colorectal cancer based on a novel immune-related long non-coding RNA prognostic signature
by: Xueliang Zhou, et al.
Published: (2022-08-01)

Genomic signature of MTOR could be an immunogenicity marker in human colorectal cancer
by: Chenxing Wang, et al.
Published: (2022-07-01)

Roles and mechanisms of tumour-infiltrating B cells in human cancer: a new force in immunotherapy
by: Enkui Zhang, et al.
Published: (2023-03-01)

Polyamine metabolism patterns characterized tumor microenvironment, prognosis, and response to immunotherapy in colorectal cancer
by: Enkui Zhang, et al.
Published: (2023-05-01)

Exploring the relationship between lactate metabolism and immunological function in colorectal cancer through genes identification and analysis
by: Enkui Zhang, et al.
Published: (2023-08-01)

Artificial Intelligence in Decision-Making for Colorectal Cancer Treatment Strategy: An Observational Study of Implementing Watson for Oncology in a 250-Case Cohort
by: Batuer Aikemu, et al.
Published: (2021-02-01)

Surgical and Non‐Surgical Treatment for 3‐Part and 4‐Part Fractures of the Proximal Humerus: A Systematic Review of Overlapping Meta‐Analyses
by: Bai‐sheng Fu, et al.
Published: (2019-06-01)

N-myc downstream-regulated gene 1 inhibits the proliferation of colorectal cancer through emulative antagonizing NEDD4-mediated ubiquitylation of p21
by: Sen Zhang, et al.
Published: (2019-12-01)

Transanal total mesorectal excision in re-operation for anastomosis recurrence rectal cancer
by: PAN Linfeng, XU Ximo, Batuer Aikemu, DENG Yang, ZHANG Sen, QIN Wei, SHU Duohuo, CAI Zhenghao, SONG Haiqin, YANG Xiao, ZHONG Hao, HU Yanyan, LI Jianwen, FENG Bo
Published: (2023-03-01)

The functional connectivity of basal forebrain is associated with superior memory performance in older adults: a case-control study
by: Shu-hong Jia, et al.
Published: (2022-06-01)

Corrigendum: Liquid chromatograph-mass spectrometry-based non-targeted metabolomics discovery of potential endogenous biomarkers associated with prostatitis rats to reveal the effects of magnoflorine
by: Yin Yuan, et al.
Published: (2022-10-01)

Liquid Chromatograph-Mass Spectrometry-Based Non-targeted Metabolomics Discovery of Potential Endogenous Biomarkers Associated With Prostatitis Rats to Reveal the Effects of Magnoflorine
by: Yin Yuan, et al.
Published: (2021-11-01)

Dynamic expression of CX36 protein in kainic acid kindling induced epilepsy
by: Wu Xue-mei, et al.
Published: (2017-05-01)

Thrombosis during hemodialysis of individuals suffered hemorrhagic fever with renal syndrome is a potential risk factor for venous thromboembolism
by: Han-Dong Zhao, et al.
Published: (2022-03-01)

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation
by: Jia Tian, et al.
Published: (2019-12-01)

Bio-Corrosion Behavior of Ceramic Coatings Containing Hydroxyapatite on Mg-Zn-Ca Magnesium Alloy
by: Hong-Yan Ding, et al.
Published: (2018-04-01)

Glutamine exerts a protective effect on osteoarthritis development by inhibiting the Jun N-terminal kinase and nuclear factor kappa-B signaling pathways
by: Lin Zhong, et al.
Published: (2022-07-01)

Plastid Phylogenomics of <i>Paeonia</i> and the Evolution of Ten Flower Types in Tree Peony
by: Wen Li, et al.
Published: (2022-11-01)

The diagnostic value of next-generation sequencing technology in sepsis
by: Xiao-guang Cao, et al.
Published: (2022-09-01)

Comparison of surgical outcomes in air versus silicone oil tamponade in rhegmatogenous retinal detachment after 25G pars plana vitrectomy
by: Xue-Mei Liang, et al.
Published: (2020-04-01)

From Polyalthia to Polyalthiopsis (Annonaceae): transfer of species enlarges a previously monotypic genus
by: Bine Xue, et al.
Published: (2020-05-01)

Seismic response of 4-legged fixed offshore structure in Malaysia due to surrounding earthquake
by: Hong, Jia Hi
Published: (2015)

Recent Progresses in Solution-Processed Tandem Organic and Quantum Dots Light-Emitting Diodes
by: Shu-Guang Meng, et al.
Published: (2022-12-01)

Synthesis of Beta-Al<sub>2</sub>O<sub>3</sub> Solid Electrolytes by Glycine-nitrate Combustion
by: ZHU Cheng-fei, et al.
Published: (2016-08-01)

2,6-Bis[1-(2-methylphenylimino)ethyl]pyridine
by: Rui-Qing Fan, et al.
Published: (2009-07-01)

Efficacy of mesenchymal stem cell therapy for sepsis: a meta-analysis of preclinical studies
by: Xue-Yi Sun, et al.
Published: (2020-06-01)

Trade-offs between coherence and mixedness and their evolution under quantum noise channels
by: Xu-Jun Che, et al.
Published: (2023-09-01)

Software watermarking scheme with cloud computing constraints
by: Guang SUN, et al.
Published: (2016-09-01)

Culture-negative chronic hematogenous osteomyelitis in a two months old girl: a case report
by: Cheng-he Qin, et al.
Published: (2021-08-01)

Tumor-secreted exosomal Wnt2B activates fibroblasts to promote cervical cancer progression
by: Luo-Jiao Liang, et al.
Published: (2021-03-01)

Lignan and Phthalide Derivatives from the Rhizome of Ligusticum chuanxiong (Rhizoma chuanxiong) and Evaluation of Their anti-Xanthine Oxidase Activities
by: Man-Li Yang, et al.
Published: (2023-10-01)

Microstructure and Mechanical Properties of Graphene Oxide/Copper Composites
by: HONG Qi-hu, et al.
Published: (2016-09-01)

Characterization of the complete chloroplast genome of ‘Yunning No.1’ lemon (Citrus limon)
by: Shao-hua Wang, et al.
Published: (2021-02-01)

PD-1 inhibitor plus anlotinib for metastatic castration-resistant prostate cancer: a real-world study
by: Xin-Xing Du, et al.
Published: (2023-01-01)

Human rabies in China: evidence-based suggestions for improved case detection and data gathering
by: Hao Li, et al.
Published: (2020-06-01)

Therapeutic effect of a traditional Chinese medicine formulation on experimental choroidal neovascularization in mouse
by: Yu-Fei Zhang, et al.
Published: (2021-10-01)

Heat transfer evaluation of natural convection outside the condenser in Passive Residual Heat Removal System of Molten Salt Reactor
by: Ding Tao, et al.
Published: (2021-12-01)

Crystal structure of diaqua-(acetato-κ3O,O′:O′′)-(μ3-4,6-di(1H-imidazol-1-yl)isophthalato-κ4O:O′:O′′,O′′′)lanthanum(III), C16H15LaN4O8
by: Liu Xue-Guo, et al.
Published: (2018-07-01)