The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers
Purpose: To provide normative data of foveal avascular zone (FAZ) and thickness. Methods: In this cross-sectional study both eyes of each normal subject were scanned with optical coherence tomography angiography (OCTA) for foveal superficial and deep avascular zone (FAZ) and central foveal thickness...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-12-01
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| Series: | Journal of Current Ophthalmology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2452232517300306 |
| _version_ | 1819052302579793920 |
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| author | Fariba Ghassemi Reza Mirshahi Fatemeh Bazvand Kaveh Fadakar Houshang Faghihi Siamak Sabour |
| author_facet | Fariba Ghassemi Reza Mirshahi Fatemeh Bazvand Kaveh Fadakar Houshang Faghihi Siamak Sabour |
| author_sort | Fariba Ghassemi |
| collection | DOAJ |
| description | Purpose: To provide normative data of foveal avascular zone (FAZ) and thickness. Methods: In this cross-sectional study both eyes of each normal subject were scanned with optical coherence tomography angiography (OCTA) for foveal superficial and deep avascular zone (FAZ) and central foveal thickness (CFT) and parafoveal thickness (PFT). Results: Out of a total of 224 eyes of 112 volunteers with a mean age of 37.03 (12â67) years, the mean superficial FAZ area was 0.27 mm2, and deep FAZ area was 0.35 mm2 (P < 0.001), with no difference between both eyes. Females had a larger superficial (0.32 ± 0.11 mm2 versus 0.23 ± 0.09 mm2) and deep FAZ (0.40 ± 0.14 mm2 versus 0.31 ± 0.10 mm2) (P < 0.001) than males. By multivariate linear regression analysis, in normal eyes, superficial FAZ area varied significantly with the gender, CFT, and deep FAZ. Deep FAZ varied with the gender and CFT. Conclusion: The gender and CFT influence the size of normal superficial and deep FAZ of capillary network. Keywords: FAZ, Fovea, Foveal avascular zone, Foveal thickness, Normal eye, Optical coherence tomography angiography |
| first_indexed | 2024-12-21T12:17:41Z |
| format | Article |
| id | doaj.art-e07cb027e4634300afadbe11efa25b96 |
| institution | Directory Open Access Journal |
| issn | 2452-2325 |
| language | English |
| last_indexed | 2024-12-21T12:17:41Z |
| publishDate | 2017-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Current Ophthalmology |
| spelling | doaj.art-e07cb027e4634300afadbe11efa25b962022-12-21T19:04:23ZengWolters Kluwer Medknow PublicationsJournal of Current Ophthalmology2452-23252017-12-01294293299The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteersFariba Ghassemi0Reza Mirshahi1Fatemeh Bazvand2Kaveh Fadakar3Houshang Faghihi4Siamak Sabour5Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; Retina & Vitreous Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; Corresponding author. Eye Research Center, Farabi Eye Hospital, Qazvin Square, Tehran, Iran.Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranEye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, IranSafety Promotion and Injury Prevention Research Center, Department of Clinical Epidemiology, Shahid Beheshti University of Medical Sciences, Tehran, IranPurpose: To provide normative data of foveal avascular zone (FAZ) and thickness. Methods: In this cross-sectional study both eyes of each normal subject were scanned with optical coherence tomography angiography (OCTA) for foveal superficial and deep avascular zone (FAZ) and central foveal thickness (CFT) and parafoveal thickness (PFT). Results: Out of a total of 224 eyes of 112 volunteers with a mean age of 37.03 (12â67) years, the mean superficial FAZ area was 0.27 mm2, and deep FAZ area was 0.35 mm2 (P < 0.001), with no difference between both eyes. Females had a larger superficial (0.32 ± 0.11 mm2 versus 0.23 ± 0.09 mm2) and deep FAZ (0.40 ± 0.14 mm2 versus 0.31 ± 0.10 mm2) (P < 0.001) than males. By multivariate linear regression analysis, in normal eyes, superficial FAZ area varied significantly with the gender, CFT, and deep FAZ. Deep FAZ varied with the gender and CFT. Conclusion: The gender and CFT influence the size of normal superficial and deep FAZ of capillary network. Keywords: FAZ, Fovea, Foveal avascular zone, Foveal thickness, Normal eye, Optical coherence tomography angiographyhttp://www.sciencedirect.com/science/article/pii/S2452232517300306 |
| spellingShingle | Fariba Ghassemi Reza Mirshahi Fatemeh Bazvand Kaveh Fadakar Houshang Faghihi Siamak Sabour The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers Journal of Current Ophthalmology |
| title | The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| title_full | The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| title_fullStr | The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| title_full_unstemmed | The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| title_short | The quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| title_sort | quantitative measurements of foveal avascular zone using optical coherence tomography angiography in normal volunteers |
| url | http://www.sciencedirect.com/science/article/pii/S2452232517300306 |
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