Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis

Plasma Lipidome, PNPLA3 polymorphism and hepatic steatosis in hereditary hemochromatosis

Abstract Background Hereditary hemochromatosis (HH) is an autosomal recessive genetic disorder with increased intestinal iron absorption and therefore iron Overload. iron overload leads to increased levels of toxic non-transferrin bound iron which results in oxidative stress and lipid peroxidation....

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Bibliographic Details
Main Authors: Jessica Seeßle, Hongying Gan-Schreier, Marietta Kirchner, Wolfgang Stremmel, Walee Chamulitrat, Uta Merle
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Gastroenterology
Subjects:
Hereditary hemochromatosis
Plasma lipidome
Phospholipids
Triglycerides
Nonalcoholic fatty liver disease
PNPLA3 polymorphism
Online Access:http://link.springer.com/article/10.1186/s12876-020-01282-3

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http://link.springer.com/article/10.1186/s12876-020-01282-3

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