Oxidative Stress in Chronic Hepatitis B—An Update
In recent years, the role of oxidative stress has been investigated in an increasing number of infections. There is a close link between the inflammation that accompanies infections and oxidative stress. Excessive reactive oxygen species induce harmful effects on cell components, including lipids, p...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/10/7/1265 |
| _version_ | 1797445101292617728 |
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| author | Gabriela Loredana Popa Mircea Ioan Popa |
| author_facet | Gabriela Loredana Popa Mircea Ioan Popa |
| author_sort | Gabriela Loredana Popa |
| collection | DOAJ |
| description | In recent years, the role of oxidative stress has been investigated in an increasing number of infections. There is a close link between the inflammation that accompanies infections and oxidative stress. Excessive reactive oxygen species induce harmful effects on cell components, including lipids, proteins, and nucleic acids. A growing body of evidence attests to the role of oxidative stress in the pathogenesis of viral liver infections, especially in hepatitis C virus (HCV) infection. Regarding hepatitis B virus (HBV) infection, the data are limited, but important progress has been achieved in recent years. This review presents the latest advances pertaining to the role of the oxidative stress byproducts in the pathogenesis of chronic hepatitis B, constituting a source of potential new markers for the evaluation and monitoring of patients with chronic hepatitis B. |
| first_indexed | 2024-03-09T13:21:50Z |
| format | Article |
| id | doaj.art-e0805297c4874f978b871f27a74e7cab |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T13:21:50Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-e0805297c4874f978b871f27a74e7cab2023-11-30T21:29:51ZengMDPI AGMicroorganisms2076-26072022-06-01107126510.3390/microorganisms10071265Oxidative Stress in Chronic Hepatitis B—An UpdateGabriela Loredana Popa0Mircea Ioan Popa1Department of Microbiology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaDepartment of Microbiology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, RomaniaIn recent years, the role of oxidative stress has been investigated in an increasing number of infections. There is a close link between the inflammation that accompanies infections and oxidative stress. Excessive reactive oxygen species induce harmful effects on cell components, including lipids, proteins, and nucleic acids. A growing body of evidence attests to the role of oxidative stress in the pathogenesis of viral liver infections, especially in hepatitis C virus (HCV) infection. Regarding hepatitis B virus (HBV) infection, the data are limited, but important progress has been achieved in recent years. This review presents the latest advances pertaining to the role of the oxidative stress byproducts in the pathogenesis of chronic hepatitis B, constituting a source of potential new markers for the evaluation and monitoring of patients with chronic hepatitis B.https://www.mdpi.com/2076-2607/10/7/1265oxidative stresshepatitis B virus infectionhepatocellular carcinomafibrosis |
| spellingShingle | Gabriela Loredana Popa Mircea Ioan Popa Oxidative Stress in Chronic Hepatitis B—An Update Microorganisms oxidative stress hepatitis B virus infection hepatocellular carcinoma fibrosis |
| title | Oxidative Stress in Chronic Hepatitis B—An Update |
| title_full | Oxidative Stress in Chronic Hepatitis B—An Update |
| title_fullStr | Oxidative Stress in Chronic Hepatitis B—An Update |
| title_full_unstemmed | Oxidative Stress in Chronic Hepatitis B—An Update |
| title_short | Oxidative Stress in Chronic Hepatitis B—An Update |
| title_sort | oxidative stress in chronic hepatitis b an update |
| topic | oxidative stress hepatitis B virus infection hepatocellular carcinoma fibrosis |
| url | https://www.mdpi.com/2076-2607/10/7/1265 |
| work_keys_str_mv | AT gabrielaloredanapopa oxidativestressinchronichepatitisbanupdate AT mirceaioanpopa oxidativestressinchronichepatitisbanupdate |