Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss

Endocannabinoid receptor blockade reduces alanine aminotransferase in polycystic ovary syndrome independent of weight loss

Abstract Background Evidence suggests that endocannabinoid system activation through the cannabinoid receptor 1 (CB1) is associated with enhanced liver injury, and CB1 antagonism may be beneficial. The aim of this study was to determine the impact of rimonabant (CB1 antagonist) on alanine aminotrans...

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Bibliographic Details
Main Authors: Alison J. Dawson, Eric S. Kilpatrick, Anne-Marie Coady, Abeer M. M. Elshewehy, Youssra Dakroury, Lina Ahmed, Stephen L. Atkin, Thozhukat Sathyapalan
Format: Article
Language:English
Published: BMC 2017-07-01
Series:BMC Endocrine Disorders
Subjects:
Alt
Rimonabant
Polycystic ovarian syndrome
Nafld
Online Access:http://link.springer.com/article/10.1186/s12902-017-0194-2

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