Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis
Objective To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. Methods PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed d...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2022-12-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/03000605221134467 |
| _version_ | 1798014240658817024 |
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| author | Peng Wang Wei Cao Hong Zhou Huan Xin Zhang Lunzhong Zhang Li Liu Yunlong Sui Zhen Zhang Xiaoyu Yin Fan Yang Li Kong |
| author_facet | Peng Wang Wei Cao Hong Zhou Huan Xin Zhang Lunzhong Zhang Li Liu Yunlong Sui Zhen Zhang Xiaoyu Yin Fan Yang Li Kong |
| author_sort | Peng Wang |
| collection | DOAJ |
| description | Objective To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. Methods PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. Results We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). Conclusions MNS may promote recovery from consciousness disorders. |
| first_indexed | 2024-04-11T15:14:17Z |
| format | Article |
| id | doaj.art-e0812b97354e4b0585c5fd73395a7d56 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-04-11T15:14:17Z |
| publishDate | 2022-12-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-e0812b97354e4b0585c5fd73395a7d562022-12-22T04:16:32ZengSAGE PublishingJournal of International Medical Research1473-23002022-12-015010.1177/03000605221134467Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysisPeng WangWei CaoHong ZhouHuan Xin ZhangLunzhong ZhangLi LiuYunlong SuiZhen ZhangXiaoyu YinFan YangLi KongObjective To identify whether median nerve stimulation (MNS) may be a potential candidate for the treatment of consciousness disorders via a systematic review and meta-analysis. Methods PubMed, Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, Wanfang, and SinoMed databases were searched. Risk of bias was assessed using the Cochrane Collaboration’s tool. The Glasgow Coma Scale (GCS), Disability Rating Scale (DRS), electroencephalogram (EEG), days in the Intensive Care Unit (ICU), and cerebral blood flow measures were compared between the median nerve stimulation and control groups. The meta-analysis was conducted using Review Manager software. Results We identified 2244 studies, of which 23 (with data from 1856 patients) qualified for the analysis. MNS improved GCS scores (mean difference [MD] = 2.15), EEG scores (MD = 1.61), cerebral mean blood flow velocity (MD = 4.23), and cerebral systolic blood flow velocity (MD = 10.51). Furthermore, it decreased DRS scores (MD = −1.77) and days in the ICU (MD = −2.02). The effects of MNS on GCS scores increased with longer treatments (1 week, MD = 1.03; 1 month, MD = 2.35) and were better with right MNS (right, MD = 2.36; bilateral, MD = 1.72). Conclusions MNS may promote recovery from consciousness disorders.https://doi.org/10.1177/03000605221134467 |
| spellingShingle | Peng Wang Wei Cao Hong Zhou Huan Xin Zhang Lunzhong Zhang Li Liu Yunlong Sui Zhen Zhang Xiaoyu Yin Fan Yang Li Kong Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis Journal of International Medical Research |
| title | Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
| title_full | Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
| title_fullStr | Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
| title_full_unstemmed | Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
| title_short | Efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders: a systematic review and meta-analysis |
| title_sort | efficacy of median nerve electrical stimulation on the recovery of patients with consciousness disorders a systematic review and meta analysis |
| url | https://doi.org/10.1177/03000605221134467 |
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