The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy
Aurum nanomaterials (ANM), combining the features of nanotechnology and metal elements, have demonstrated enormous potential and aroused great attention on biomedical applications over the past few decades. Particularly, their advantages, such as controllable particle size, flexible surface modifica...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2019-07-01
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| Series: | Asian Journal of Pharmaceutical Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1818087618302538 |
| _version_ | 1811201434079723520 |
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| author | Dan Yang Feiyang Deng Dechun Liu Bo He Bing He Xing Tang Qiang Zhang |
| author_facet | Dan Yang Feiyang Deng Dechun Liu Bo He Bing He Xing Tang Qiang Zhang |
| author_sort | Dan Yang |
| collection | DOAJ |
| description | Aurum nanomaterials (ANM), combining the features of nanotechnology and metal elements, have demonstrated enormous potential and aroused great attention on biomedical applications over the past few decades. Particularly, their advantages, such as controllable particle size, flexible surface modification, higher drug loading, good stability and biocompatibility, especially unique optical properties, promote the development of ANM in biomedical field. In this review, we will discuss the advanced preparation process of ANM and summarize their recent applications as well as their prospects in diagnosis and therapy. Besides, multi-functional ANM-based theranostic nanosystems will be introduced in details, including radiotherapy (RT), photothermal therapy (PTT), photodynamic therapy (PDT), immunotherapy (IT), and so on. Keywords: Gold nanomaterials, Imaging and biodiagnostics, Drug delivery, Photothermal therapy, Immunotherapy, Combination therapy |
| first_indexed | 2024-04-12T02:21:39Z |
| format | Article |
| id | doaj.art-e081acda1005491996979630c9a925e8 |
| institution | Directory Open Access Journal |
| issn | 1818-0876 |
| language | English |
| last_indexed | 2024-04-12T02:21:39Z |
| publishDate | 2019-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-e081acda1005491996979630c9a925e82022-12-22T03:52:07ZengElsevierAsian Journal of Pharmaceutical Sciences1818-08762019-07-01144349364The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapyDan Yang0Feiyang Deng1Dechun Liu2Bo He3Bing He4Xing Tang5Qiang Zhang6School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, ChinaBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, ChinaBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, ChinaBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, ChinaBeijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, ChinaSchool of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; Corresponding authors. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Tel.: +86 24 23986343 (X. Tang), +86 10 82802791 (Q. Zhang).School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China; Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China; State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China; Corresponding authors. School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Tel.: +86 24 23986343 (X. Tang), +86 10 82802791 (Q. Zhang).Aurum nanomaterials (ANM), combining the features of nanotechnology and metal elements, have demonstrated enormous potential and aroused great attention on biomedical applications over the past few decades. Particularly, their advantages, such as controllable particle size, flexible surface modification, higher drug loading, good stability and biocompatibility, especially unique optical properties, promote the development of ANM in biomedical field. In this review, we will discuss the advanced preparation process of ANM and summarize their recent applications as well as their prospects in diagnosis and therapy. Besides, multi-functional ANM-based theranostic nanosystems will be introduced in details, including radiotherapy (RT), photothermal therapy (PTT), photodynamic therapy (PDT), immunotherapy (IT), and so on. Keywords: Gold nanomaterials, Imaging and biodiagnostics, Drug delivery, Photothermal therapy, Immunotherapy, Combination therapyhttp://www.sciencedirect.com/science/article/pii/S1818087618302538 |
| spellingShingle | Dan Yang Feiyang Deng Dechun Liu Bo He Bing He Xing Tang Qiang Zhang The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy Asian Journal of Pharmaceutical Sciences |
| title | The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy |
| title_full | The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy |
| title_fullStr | The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy |
| title_full_unstemmed | The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy |
| title_short | The appliances and prospects of aurum nanomaterials in biodiagnostics, imaging, drug delivery and combination therapy |
| title_sort | appliances and prospects of aurum nanomaterials in biodiagnostics imaging drug delivery and combination therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1818087618302538 |
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