Biodegradable Metal Complex-Gated Organosilica for Dually Enhanced Chemodynamic Therapy through GSH Depletions and NIR Light-Triggered Photothermal Effects

Biodegradable Metal Complex-Gated Organosilica for Dually Enhanced Chemodynamic Therapy through GSH Depletions and NIR Light-Triggered Photothermal Effects

Hollow silica spheres have been widely studied for drug delivery because of their excellent biosecurity and high porosity. However, difficulties with degradation in the tumor microenvironment (TME) and premature leaking during drug delivery limit their clinical applications. To alleviate these probl...

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Bibliographic Details
Main Authors: Lin Kong, Jian Li, Yunxiu Zhang, Jian Wang, Ke Liang, Xiaokuang Xue, Tiejin Chen, Yongliang Hao, Haohui Ren, Pengfei Wang, Jiechao Ge
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
biodegradable organosilica
chemodynamic therapy
GSH depletion
photothermal effect enhancement
Online Access:https://www.mdpi.com/1420-3049/29/5/1177

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