Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
Abstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies...
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Nature Portfolio
2023-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-39438-2 |
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author | Zhe Xiong Kuangjing Wang Huahui Zhang Ying Fang Fengdong Li Jin Huang |
author_facet | Zhe Xiong Kuangjing Wang Huahui Zhang Ying Fang Fengdong Li Jin Huang |
author_sort | Zhe Xiong |
collection | DOAJ |
description | Abstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies procedures were included. The individual sensitivity, specificity, and accuracy were analyzed. A total of 67 patients were enrolled in this multi-center retrospective study. The DSOC and improved fluoroscopy-guided biopsies procedures were successfully performed in all cases (100%). The sensitivity, specificity, and accuracy values were 83.3%, 89.5%, and 85.1% for DSOC visual impression; 95.8%, 94.7%, and 95.5% for improved fluoroscopy-guided biopsies procedures, respectively. The sensitivity and accuracy of improved fluoroscopy-guided biopsies were significantly higher compared with DSOC visual impression. Four patients (6.0%, 4/67) occurred adverse events after the procedures. Improved fluoroscopy-guided biopsies had a high diagnostic accuracy of IBDS diagnosis. |
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id | doaj.art-e085f3ebea604d4a87cb51e753fd67d0 |
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issn | 2045-2322 |
language | English |
last_indexed | 2024-03-10T17:55:24Z |
publishDate | 2023-08-01 |
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series | Scientific Reports |
spelling | doaj.art-e085f3ebea604d4a87cb51e753fd67d02023-11-20T09:13:44ZengNature PortfolioScientific Reports2045-23222023-08-011311710.1038/s41598-023-39438-2Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective studyZhe Xiong0Kuangjing Wang1Huahui Zhang2Ying Fang3Fengdong Li4Jin Huang5Department of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, The People’s Hospital of Ma AnshanDepartment of Gastroenterology, The First People’s Hospital of LianyungangDepartment of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, Changzhou No.2 People’s HospitalAbstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies procedures were included. The individual sensitivity, specificity, and accuracy were analyzed. A total of 67 patients were enrolled in this multi-center retrospective study. The DSOC and improved fluoroscopy-guided biopsies procedures were successfully performed in all cases (100%). The sensitivity, specificity, and accuracy values were 83.3%, 89.5%, and 85.1% for DSOC visual impression; 95.8%, 94.7%, and 95.5% for improved fluoroscopy-guided biopsies procedures, respectively. The sensitivity and accuracy of improved fluoroscopy-guided biopsies were significantly higher compared with DSOC visual impression. Four patients (6.0%, 4/67) occurred adverse events after the procedures. Improved fluoroscopy-guided biopsies had a high diagnostic accuracy of IBDS diagnosis.https://doi.org/10.1038/s41598-023-39438-2 |
spellingShingle | Zhe Xiong Kuangjing Wang Huahui Zhang Ying Fang Fengdong Li Jin Huang Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study Scientific Reports |
title | Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study |
title_full | Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study |
title_fullStr | Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study |
title_full_unstemmed | Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study |
title_short | Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study |
title_sort | improved fluoroscopy guided biopsies in the diagnosis of indeterminate biliary strictures a multi center retrospective study |
url | https://doi.org/10.1038/s41598-023-39438-2 |
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