Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study

Abstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies...

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Main Authors: Zhe Xiong, Kuangjing Wang, Huahui Zhang, Ying Fang, Fengdong Li, Jin Huang
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-39438-2
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author Zhe Xiong
Kuangjing Wang
Huahui Zhang
Ying Fang
Fengdong Li
Jin Huang
author_facet Zhe Xiong
Kuangjing Wang
Huahui Zhang
Ying Fang
Fengdong Li
Jin Huang
author_sort Zhe Xiong
collection DOAJ
description Abstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies procedures were included. The individual sensitivity, specificity, and accuracy were analyzed. A total of 67 patients were enrolled in this multi-center retrospective study. The DSOC and improved fluoroscopy-guided biopsies procedures were successfully performed in all cases (100%). The sensitivity, specificity, and accuracy values were 83.3%, 89.5%, and 85.1% for DSOC visual impression; 95.8%, 94.7%, and 95.5% for improved fluoroscopy-guided biopsies procedures, respectively. The sensitivity and accuracy of improved fluoroscopy-guided biopsies were significantly higher compared with DSOC visual impression. Four patients (6.0%, 4/67) occurred adverse events after the procedures. Improved fluoroscopy-guided biopsies had a high diagnostic accuracy of IBDS diagnosis.
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spelling doaj.art-e085f3ebea604d4a87cb51e753fd67d02023-11-20T09:13:44ZengNature PortfolioScientific Reports2045-23222023-08-011311710.1038/s41598-023-39438-2Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective studyZhe Xiong0Kuangjing Wang1Huahui Zhang2Ying Fang3Fengdong Li4Jin Huang5Department of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, The People’s Hospital of Ma AnshanDepartment of Gastroenterology, The First People’s Hospital of LianyungangDepartment of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, Changzhou No.2 People’s HospitalDepartment of Gastroenterology, Changzhou No.2 People’s HospitalAbstract To evaluate the diagnostic accuracy of improved fluoroscopy-guided biopsies for indeterminate biliary strictures (IBDS). A multi-center retrospective study was performed. Patients with IBDS who underwent digital single-operator cholangioscopy (DSOC) and improved fluoroscopy-guided biopsies procedures were included. The individual sensitivity, specificity, and accuracy were analyzed. A total of 67 patients were enrolled in this multi-center retrospective study. The DSOC and improved fluoroscopy-guided biopsies procedures were successfully performed in all cases (100%). The sensitivity, specificity, and accuracy values were 83.3%, 89.5%, and 85.1% for DSOC visual impression; 95.8%, 94.7%, and 95.5% for improved fluoroscopy-guided biopsies procedures, respectively. The sensitivity and accuracy of improved fluoroscopy-guided biopsies were significantly higher compared with DSOC visual impression. Four patients (6.0%, 4/67) occurred adverse events after the procedures. Improved fluoroscopy-guided biopsies had a high diagnostic accuracy of IBDS diagnosis.https://doi.org/10.1038/s41598-023-39438-2
spellingShingle Zhe Xiong
Kuangjing Wang
Huahui Zhang
Ying Fang
Fengdong Li
Jin Huang
Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
Scientific Reports
title Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
title_full Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
title_fullStr Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
title_full_unstemmed Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
title_short Improved fluoroscopy-guided biopsies in the diagnosis of indeterminate biliary strictures: a multi-center retrospective study
title_sort improved fluoroscopy guided biopsies in the diagnosis of indeterminate biliary strictures a multi center retrospective study
url https://doi.org/10.1038/s41598-023-39438-2
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