Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia
Bedaquiline is currently a key drug for treating multidrug-resistant or rifampin-resistant tuberculosis. We report and discuss the unusual development of resistance to bedaquiline in a teenager in Namibia, despite an optimal background regimen and adherence. The report highlights the risk for bedaq...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2024-03-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/30/3/24-0134_article |
| _version_ | 1797299324644753408 |
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| author | Gunar Günther Lusia Mhuulu Azaria Diergaardt Viola Dreyer Maria Moses Kaarna Anyolo Nunurai Ruswa Mareli Claassens Stefan Niemann Emmanuel Nepolo |
| author_facet | Gunar Günther Lusia Mhuulu Azaria Diergaardt Viola Dreyer Maria Moses Kaarna Anyolo Nunurai Ruswa Mareli Claassens Stefan Niemann Emmanuel Nepolo |
| author_sort | Gunar Günther |
| collection | DOAJ |
| description |
Bedaquiline is currently a key drug for treating multidrug-resistant or rifampin-resistant tuberculosis. We report and discuss the unusual development of resistance to bedaquiline in a teenager in Namibia, despite an optimal background regimen and adherence. The report highlights the risk for bedaquiline resistance development and the need for rapid drug-resistance testing.
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| first_indexed | 2024-03-07T22:48:58Z |
| format | Article |
| id | doaj.art-e08695d4891141e28060b84775cfc62b |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-03-07T22:48:58Z |
| publishDate | 2024-03-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-e08695d4891141e28060b84775cfc62b2024-02-23T14:01:43ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592024-03-0130356857110.3201/eid3003.240134Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, NamibiaGunar GüntherLusia MhuuluAzaria DiergaardtViola DreyerMaria MosesKaarna AnyoloNunurai RuswaMareli ClaassensStefan NiemannEmmanuel Nepolo Bedaquiline is currently a key drug for treating multidrug-resistant or rifampin-resistant tuberculosis. We report and discuss the unusual development of resistance to bedaquiline in a teenager in Namibia, despite an optimal background regimen and adherence. The report highlights the risk for bedaquiline resistance development and the need for rapid drug-resistance testing. https://wwwnc.cdc.gov/eid/article/30/3/24-0134_articletuberculosisTBtuberculosis and other mycobacteriabacteriarespiratory infectionsbedaquiline |
| spellingShingle | Gunar Günther Lusia Mhuulu Azaria Diergaardt Viola Dreyer Maria Moses Kaarna Anyolo Nunurai Ruswa Mareli Claassens Stefan Niemann Emmanuel Nepolo Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia Emerging Infectious Diseases tuberculosis TB tuberculosis and other mycobacteria bacteria respiratory infections bedaquiline |
| title | Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia |
| title_full | Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia |
| title_fullStr | Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia |
| title_full_unstemmed | Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia |
| title_short | Bedaquiline Resistance after Effective Treatment of Multidrug-Resistant Tuberculosis, Namibia |
| title_sort | bedaquiline resistance after effective treatment of multidrug resistant tuberculosis namibia |
| topic | tuberculosis TB tuberculosis and other mycobacteria bacteria respiratory infections bedaquiline |
| url | https://wwwnc.cdc.gov/eid/article/30/3/24-0134_article |
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