Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells

Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells

Gluconasturtiin, a glucosinolate present in watercress, is hydrolysed by myrosinase to form gluconasturtiin-isothiocyanate (GNST-ITC), which has potential chemopreventive effects; however, the underlying mechanisms of action have not been explored, mainly in human cell lines. The purpose of the stud...

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Bibliographic Details
Main Authors: Asvinidevi Arumugam, Muhammad Din Ibrahim, Saie Brindha Kntayya, Nooraini Mohd Ain, Renato Iori, Stefania Galletti, Costas Ioannides, Ahmad Faizal Abdull Razis
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
glucosinolate
gluconasturtiin-isothiocyanate
apoptosis
cancer chemoprevention
Online Access:https://www.mdpi.com/1420-3049/25/5/1240

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