Targeted Glioblastoma Treatment via Synthesis and Functionalization of Gold Nanoparticles With De Novo–Engineered Transferrin-Like Peptides: Protocol for a Novel Method
BackgroundGlioblastoma multiforme (GBM) is an aggressive brain tumor with limited treatment options due to the blood-brain barrier’s (BBB’s) impedance and inherent resistance to chemotherapy. Gold nanoparticles (AuNPs) functionalized with transferrin-like peptides show promis...
Main Authors: | Augusto Müller Fiedler, Michelle Medeiros, Haidi Dalinda Fiedler |
---|---|
Format: | Article |
Language: | English |
Published: |
JMIR Publications
2023-08-01
|
Series: | JMIR Research Protocols |
Online Access: | https://www.researchprotocols.org/2023/1/e49417 |
Similar Items
-
Engineering Peptide Inhibitors of the HFE–Transferrin Receptor 1 Complex
by: Daniela Goncalves Monteiro, et al.
Published: (2022-10-01) -
Kinetic Effects of Transferrin-Conjugated Gold Nanoparticles on the Antioxidant Glutathione-Thioredoxin Pathway
by: Sonia Sebastian, et al.
Published: (2023-08-01) -
Transferrin-Targeted Liposomes in Glioblastoma Therapy: A Review
by: Paul Kawak, et al.
Published: (2023-08-01) -
Transferrin Receptor-Targeted Nanocarriers: Overcoming Barriers to Treat Glioblastoma
by: Maria João Ramalho, et al.
Published: (2022-01-01) -
Comparison of polypeptides that bind the transferrin receptor for targeting gold nanocarriers.
by: Conor McQuaid, et al.
Published: (2021-01-01)