The Effects of Thiamine on Breast Cancer Cells

The Effects of Thiamine on Breast Cancer Cells

(1) Background: Thiamine is an important cofactor for multiple metabolic processes. Its role in cancer has been debated for years. Our aim is to determine if thiamine can convert the cellular metabolic state of breast cancer cells from anaerobic to aerobic, thus reducing their growth. (2) Methods: B...

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Bibliographic Details
Main Authors: Xiaowen Liu, Sophia Montissol, Amy Uber, Sarah Ganley, Anne V. Grossestreuer, Katherine Berg, Stanley Heydrick, Michael W. Donnino
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
thiamine
breast cancer
aerobic glycolysis
aerobic metabolism
proliferation
apoptosis
Online Access:http://www.mdpi.com/1420-3049/23/6/1464

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