Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island
Aim: The aim of this study is to evaluate the ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus (HZO). Design: This was an observational and retrospective study. Methods: All clinically diagnosed cases were included in the study. All were su...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
|
| Series: | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
| Subjects: | |
| Online Access: | http://www.mjdrdypv.org/article.asp?issn=2589-8302;year=2019;volume=12;issue=3;spage=250;epage=255;aulast=Das |
| _version_ | 1818539198547755008 |
|---|---|
| author | Sujit Das B Pradeep Chhanda Mandal |
| author_facet | Sujit Das B Pradeep Chhanda Mandal |
| author_sort | Sujit Das |
| collection | DOAJ |
| description | Aim: The aim of this study is to evaluate the ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus (HZO). Design: This was an observational and retrospective study. Methods: All clinically diagnosed cases were included in the study. All were subjected to corneal staining, corneal sensation, best-corrected visual acuity (BCVA), intraocular pressure, and fundus examination. All were treated with oral acyclovir (800 mg) 1 tablet 5 times a day for 5 days along with tablet pregabalin (150 mg twice/day) and neurobion forte (1 tablet/day). Acyclovir eye ointment was given 5 times a day for 14 days with antibiotic and cycloplegic drops. Mean follow-up was 12 months. Results: Mean age of presentation was 51–55 years (40%) with male predominance (88.6%). Unilateral eye involvement was 32 (91.4%) and bilateral was three (8.6%). Blepharitis was (80%) the most common ocular involvement followed by punctuate keratitis (77.1). Ocular complications were neurotrophic keratopathy (5.7%), corneal opacity (5.7%), and postherpetic neuralgia (62.9%). Mean BCVA was 20/20 in 33 eyes (94.3%). The sensitivity of acyclovir was found 100%. Conclusion: Rapid diagnosis and early institution of antiviral therapy are necessary to prevent ocular morbidity. History of chickenpox, low immunity, and environmental factors (hot climate, humidity, and rainfall,) greatly influences the occurrence of HZO. The overall visual outcome is good with early institution of antiviral therapy. |
| first_indexed | 2024-12-11T21:38:53Z |
| format | Article |
| id | doaj.art-e096ccbdda9441b99cc10dd052cda4bf |
| institution | Directory Open Access Journal |
| issn | 2589-8302 2589-8310 |
| language | English |
| last_indexed | 2024-12-11T21:38:53Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Dr. D.Y. Patil Vidyapeeth |
| spelling | doaj.art-e096ccbdda9441b99cc10dd052cda4bf2022-12-22T00:49:55ZengWolters Kluwer Medknow PublicationsMedical Journal of Dr. D.Y. Patil Vidyapeeth2589-83022589-83102019-01-0112325025510.4103/mjdrdypu.mjdrdypu_87_18Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar IslandSujit DasB PradeepChhanda MandalAim: The aim of this study is to evaluate the ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus (HZO). Design: This was an observational and retrospective study. Methods: All clinically diagnosed cases were included in the study. All were subjected to corneal staining, corneal sensation, best-corrected visual acuity (BCVA), intraocular pressure, and fundus examination. All were treated with oral acyclovir (800 mg) 1 tablet 5 times a day for 5 days along with tablet pregabalin (150 mg twice/day) and neurobion forte (1 tablet/day). Acyclovir eye ointment was given 5 times a day for 14 days with antibiotic and cycloplegic drops. Mean follow-up was 12 months. Results: Mean age of presentation was 51–55 years (40%) with male predominance (88.6%). Unilateral eye involvement was 32 (91.4%) and bilateral was three (8.6%). Blepharitis was (80%) the most common ocular involvement followed by punctuate keratitis (77.1). Ocular complications were neurotrophic keratopathy (5.7%), corneal opacity (5.7%), and postherpetic neuralgia (62.9%). Mean BCVA was 20/20 in 33 eyes (94.3%). The sensitivity of acyclovir was found 100%. Conclusion: Rapid diagnosis and early institution of antiviral therapy are necessary to prevent ocular morbidity. History of chickenpox, low immunity, and environmental factors (hot climate, humidity, and rainfall,) greatly influences the occurrence of HZO. The overall visual outcome is good with early institution of antiviral therapy.http://www.mjdrdypv.org/article.asp?issn=2589-8302;year=2019;volume=12;issue=3;spage=250;epage=255;aulast=DasHerpes zosterherpes zoster ophthalmicusherpetic eye diseasekeratitiskeratouveitisvaricella zoster virus-uveitis |
| spellingShingle | Sujit Das B Pradeep Chhanda Mandal Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island Medical Journal of Dr. D.Y. Patil Vidyapeeth Herpes zoster herpes zoster ophthalmicus herpetic eye disease keratitis keratouveitis varicella zoster virus-uveitis |
| title | Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island |
| title_full | Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island |
| title_fullStr | Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island |
| title_full_unstemmed | Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island |
| title_short | Ocular involvements, its complications, visual outcome, and treatment response of herpes zoster ophthalmicus: Review of 35 patients from Andaman and Nicobar Island |
| title_sort | ocular involvements its complications visual outcome and treatment response of herpes zoster ophthalmicus review of 35 patients from andaman and nicobar island |
| topic | Herpes zoster herpes zoster ophthalmicus herpetic eye disease keratitis keratouveitis varicella zoster virus-uveitis |
| url | http://www.mjdrdypv.org/article.asp?issn=2589-8302;year=2019;volume=12;issue=3;spage=250;epage=255;aulast=Das |
| work_keys_str_mv | AT sujitdas ocularinvolvementsitscomplicationsvisualoutcomeandtreatmentresponseofherpeszosterophthalmicusreviewof35patientsfromandamanandnicobarisland AT bpradeep ocularinvolvementsitscomplicationsvisualoutcomeandtreatmentresponseofherpeszosterophthalmicusreviewof35patientsfromandamanandnicobarisland AT chhandamandal ocularinvolvementsitscomplicationsvisualoutcomeandtreatmentresponseofherpeszosterophthalmicusreviewof35patientsfromandamanandnicobarisland |