Cardiolipin externalization mediates prion protein (PrP) peptide 106–126-associated mitophagy and mitochondrial dysfunction

Cardiolipin externalization mediates prion protein (PrP) peptide 106–126-associated mitophagy and mitochondrial dysfunction

Proper mitochondrial performance is imperative for the maintenance of normal neuronal function to prevent the development of neurodegenerative diseases. Persistent accumulation of damaged mitochondria plays a role in prion disease pathogenesis, which involves a chain of events that culminate in the...

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Bibliographic Details
Main Authors: Dongming Yang, Jie Li, Zhiping Li, Mengyang Zhao, Dongdong Wang, Zhixin Sun, Pei Wen, Fengting Gou, Yuexin Dai, Yilan Ji, Wen Li, Deming Zhao, Lifeng Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
mitophagy
autophagy
cardiolipin
prion disease
neurodegenerative disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1163981/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2023.1163981/full

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