Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling

Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling

Uveal melanoma (UM) is the most common primary adult intraocular malignancy. This rare but devastating cancer causes vision loss and confers a poor survival rate due to distant metastases. Identifying clinical and molecular features that portend a metastatic risk is an important part of UM workup an...

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Bibliographic Details
Main Authors: Mona Meng Wang, Chuanfei Chen, Myoe Naing Lynn, Carlos R. Figueiredo, Wei Jian Tan, Tong Seng Lim, Sarah E. Coupland, Anita Sook Yee Chan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Molecular Biosciences
Subjects:
uveal melanoma
single-cell analysis
DEPArray NxT technology
CellSearch
circulating tumor cells
FFPE
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2020.611584/full

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