MGLL deficiency in tumor-associated macrophages promotes immunosuppression and colorectal peritoneal metastases in mice

MGLL deficiency in tumor-associated macrophages promotes immunosuppression and colorectal peritoneal metastases in mice

Objective To investigate the effects and mechanisms of monoacylglycerol lipase (MGLL) in tumor-associated macrophages (TAMs) for the progression of colorectal cancer peritoneal metastases (CRC-PM). Methods After macrophage MGLL conditional knockout (cKO) mice was constructed, a CRC-PM model was esta...

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Bibliographic Details
Main Authors: YUAN Jing, MIAO Hongming
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-03-01
Series:陆军军医大学学报
Subjects:
tumor-associated macrophages
monoacylglycerol lipase
colorectal cancer
peritoneal metastases
Online Access:http://aammt.tmmu.edu.cn/html/202209246.htm

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