<i>PCSK3</i> Overexpression in Sjögren’s Syndrome Patients May Be Regulated by rs4932178 SNP in Its Promoter Region and Correlates with <i>IFN-γ</i> Gene Expression
Background: The <i>PCSK3</i> gene encodes for the protease enzyme Furin, which promotes proteolytic maturation of important regulators of the immune response, and also enhances the secretion of interferon-γ (IFN). Several studies have suggested its possible involvement in the pathogenesi...
Main Authors: | Andrea Latini, Giada De Benedittis, Serena Colafrancesco, Carlo Perricone, Giuseppe Novelli, Lucia Novelli, Roberta Priori, Cinzia Ciccacci, Paola Borgiani |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/14/5/981 |
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