Methotrexate-induced lung damage in a patient with rheumatoid arthritis

We herein report a case of interstitial lung disease secondary to the use of methotrexate in a patient with rheumatoid arthritis. Differential diagnosis between pneumonitis caused by methotrexate in patients treated with basic methotrexate therapy and interstitial pulmonary disease associated with r...

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Main Authors: Liubov A. Ponomareva, Daria V. Gurova, Elena N. Popova, Natalia V. Chebotareva, Inna B. Bondarenko, Sergey V. Moiseev
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2021-03-01
Series:Терапевтический архив
Subjects:
Online Access:https://ter-arkhiv.ru/0040-3660/article/viewFile/64973/47826
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author Liubov A. Ponomareva
Daria V. Gurova
Elena N. Popova
Natalia V. Chebotareva
Inna B. Bondarenko
Sergey V. Moiseev
author_facet Liubov A. Ponomareva
Daria V. Gurova
Elena N. Popova
Natalia V. Chebotareva
Inna B. Bondarenko
Sergey V. Moiseev
author_sort Liubov A. Ponomareva
collection DOAJ
description We herein report a case of interstitial lung disease secondary to the use of methotrexate in a patient with rheumatoid arthritis. Differential diagnosis between pneumonitis caused by methotrexate in patients treated with basic methotrexate therapy and interstitial pulmonary disease associated with rheumatoid arthritis is based on the clinical examination and instrumental data. The main condition for favorable clinical outcome in all drug-induced lung disease is drug withdrawal, what was proven in our report.
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spelling doaj.art-e0a4347079624c70b785115689082a7b2022-12-21T18:45:53Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422021-03-0193329529910.26442/00403660.2021.03.20065659398Methotrexate-induced lung damage in a patient with rheumatoid arthritisLiubov A. Ponomareva0https://orcid.org/0000-0002-3179-470XDaria V. Gurova1https://orcid.org/0000-0001-8232-3679Elena N. Popova2https://orcid.org/0000-0001-5164-4621Natalia V. Chebotareva3https://orcid.org/0000-0002-4111-1175Inna B. Bondarenko4https://orcid.org/0000-0002-4111-1175Sergey V. Moiseev5https://orcid.org/0000-0002-7232-4640Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)Sechenov First Moscow State Medical University (Sechenov University)We herein report a case of interstitial lung disease secondary to the use of methotrexate in a patient with rheumatoid arthritis. Differential diagnosis between pneumonitis caused by methotrexate in patients treated with basic methotrexate therapy and interstitial pulmonary disease associated with rheumatoid arthritis is based on the clinical examination and instrumental data. The main condition for favorable clinical outcome in all drug-induced lung disease is drug withdrawal, what was proven in our report.https://ter-arkhiv.ru/0040-3660/article/viewFile/64973/47826methotrexaterheumatoid arthritispulmonary fibrosisdrug-induced lung disease
spellingShingle Liubov A. Ponomareva
Daria V. Gurova
Elena N. Popova
Natalia V. Chebotareva
Inna B. Bondarenko
Sergey V. Moiseev
Methotrexate-induced lung damage in a patient with rheumatoid arthritis
Терапевтический архив
methotrexate
rheumatoid arthritis
pulmonary fibrosis
drug-induced lung disease
title Methotrexate-induced lung damage in a patient with rheumatoid arthritis
title_full Methotrexate-induced lung damage in a patient with rheumatoid arthritis
title_fullStr Methotrexate-induced lung damage in a patient with rheumatoid arthritis
title_full_unstemmed Methotrexate-induced lung damage in a patient with rheumatoid arthritis
title_short Methotrexate-induced lung damage in a patient with rheumatoid arthritis
title_sort methotrexate induced lung damage in a patient with rheumatoid arthritis
topic methotrexate
rheumatoid arthritis
pulmonary fibrosis
drug-induced lung disease
url https://ter-arkhiv.ru/0040-3660/article/viewFile/64973/47826
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