Medical Devices for Tremor Suppression: Current Status and Future Directions
Tremors are the most prevalent movement disorder that interferes with the patient’s daily living, and physical activities, ultimately leading to a reduced quality of life. Due to the pathophysiology of tremor, developing effective pharmacotherapies, which are only suboptimal in the management of tre...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/11/4/99 |
| _version_ | 1797539645654827008 |
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| author | Jiancheng Mo Ronny Priefer |
| author_facet | Jiancheng Mo Ronny Priefer |
| author_sort | Jiancheng Mo |
| collection | DOAJ |
| description | Tremors are the most prevalent movement disorder that interferes with the patient’s daily living, and physical activities, ultimately leading to a reduced quality of life. Due to the pathophysiology of tremor, developing effective pharmacotherapies, which are only suboptimal in the management of tremor, has many challenges. Thus, a range of therapies are necessary in managing this progressive, aging-associated disorder. Surgical interventions such as deep brain stimulation are able to provide durable tremor control. However, due to high costs, patient and practitioner preference, and perceived high risks, their utilization is minimized. Medical devices are placed in a unique position to bridge this gap between lifestyle interventions, pharmacotherapies, and surgical treatments to provide safe and effective tremor suppression. Herein, we review the mechanisms of action, safety and efficacy profiles, and clinical applications of different medical devices that are currently available or have been previously investigated for tremor suppression. These devices are primarily noninvasive, which can be a beneficial addition to the patient’s existing pharmacotherapy and/or lifestyle intervention. |
| first_indexed | 2024-03-10T12:47:53Z |
| format | Article |
| id | doaj.art-e0a6db0ef97f4a9da8229097d80a212d |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-10T12:47:53Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-e0a6db0ef97f4a9da8229097d80a212d2023-11-21T13:20:07ZengMDPI AGBiosensors2079-63742021-03-011149910.3390/bios11040099Medical Devices for Tremor Suppression: Current Status and Future DirectionsJiancheng Mo0Ronny Priefer1Massachusetts College of Pharmacy and Health Sciences University, School of Pharmacy, Boston, MA 02115, USAMassachusetts College of Pharmacy and Health Sciences University, School of Pharmacy, Boston, MA 02115, USATremors are the most prevalent movement disorder that interferes with the patient’s daily living, and physical activities, ultimately leading to a reduced quality of life. Due to the pathophysiology of tremor, developing effective pharmacotherapies, which are only suboptimal in the management of tremor, has many challenges. Thus, a range of therapies are necessary in managing this progressive, aging-associated disorder. Surgical interventions such as deep brain stimulation are able to provide durable tremor control. However, due to high costs, patient and practitioner preference, and perceived high risks, their utilization is minimized. Medical devices are placed in a unique position to bridge this gap between lifestyle interventions, pharmacotherapies, and surgical treatments to provide safe and effective tremor suppression. Herein, we review the mechanisms of action, safety and efficacy profiles, and clinical applications of different medical devices that are currently available or have been previously investigated for tremor suppression. These devices are primarily noninvasive, which can be a beneficial addition to the patient’s existing pharmacotherapy and/or lifestyle intervention.https://www.mdpi.com/2079-6374/11/4/99tremormedical devicestranscutaneous electrical nerve stimulationelectrical stimulation systemswearable orthosesassistive feeding devices |
| spellingShingle | Jiancheng Mo Ronny Priefer Medical Devices for Tremor Suppression: Current Status and Future Directions Biosensors tremor medical devices transcutaneous electrical nerve stimulation electrical stimulation systems wearable orthoses assistive feeding devices |
| title | Medical Devices for Tremor Suppression: Current Status and Future Directions |
| title_full | Medical Devices for Tremor Suppression: Current Status and Future Directions |
| title_fullStr | Medical Devices for Tremor Suppression: Current Status and Future Directions |
| title_full_unstemmed | Medical Devices for Tremor Suppression: Current Status and Future Directions |
| title_short | Medical Devices for Tremor Suppression: Current Status and Future Directions |
| title_sort | medical devices for tremor suppression current status and future directions |
| topic | tremor medical devices transcutaneous electrical nerve stimulation electrical stimulation systems wearable orthoses assistive feeding devices |
| url | https://www.mdpi.com/2079-6374/11/4/99 |
| work_keys_str_mv | AT jianchengmo medicaldevicesfortremorsuppressioncurrentstatusandfuturedirections AT ronnypriefer medicaldevicesfortremorsuppressioncurrentstatusandfuturedirections |