Etiology, pathogenesis, and diagnosis of neovascular glaucoma
Neovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glauc...
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Format: | Article |
Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-06-01
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Series: | International Journal of Ophthalmology |
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Online Access: | http://ies.ijo.cn/en_publish/2022/6/20220620.pdf |
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author | Dan Calugaru Mihai Calugaru |
author_facet | Dan Calugaru Mihai Calugaru |
author_sort | Dan Calugaru |
collection | DOAJ |
description | Neovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glaucoma are diabetic retinopathy, ischemic central retinal vein occlusion, and ocular ischemic syndrome. Uncommon causes include ocular radiation, ocular tumors, uveitis and other miscellaneous conditions. Vascular endothelial growth factor is an important and likely predominant agent involved in the pathogenesis of intraocular neovascularization and neovascular glaucoma. The evolution of clinical and histopathological changes from predisposing conditions to the occurrence of rubeosis iridis and neovascular glaucoma is divided into four stages: prerubeosis, preglaucoma, open angle glaucoma, and angle-closure glaucoma. |
first_indexed | 2024-04-14T05:15:51Z |
format | Article |
id | doaj.art-e0a831956bf4437b8b6c926c640c149b |
institution | Directory Open Access Journal |
issn | 2222-3959 2227-4898 |
language | English |
last_indexed | 2024-04-14T05:15:51Z |
publishDate | 2022-06-01 |
publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
record_format | Article |
series | International Journal of Ophthalmology |
spelling | doaj.art-e0a831956bf4437b8b6c926c640c149b2022-12-22T02:10:22ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-06-011561005101010.18240/ijo.2022.06.2020220620Etiology, pathogenesis, and diagnosis of neovascular glaucomaDan Calugaru0Mihai Calugaru1Mihai Călugăru. Strada Brâncoveanu 11, Cluj-Napoca 400467, Romania. mihai.calugaru@mail.dntcj.roDepartment of Ophthalmology, University of Medicine, Cluj-Napoca 400467, RomaniaNeovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glaucoma are diabetic retinopathy, ischemic central retinal vein occlusion, and ocular ischemic syndrome. Uncommon causes include ocular radiation, ocular tumors, uveitis and other miscellaneous conditions. Vascular endothelial growth factor is an important and likely predominant agent involved in the pathogenesis of intraocular neovascularization and neovascular glaucoma. The evolution of clinical and histopathological changes from predisposing conditions to the occurrence of rubeosis iridis and neovascular glaucoma is divided into four stages: prerubeosis, preglaucoma, open angle glaucoma, and angle-closure glaucoma.http://ies.ijo.cn/en_publish/2022/6/20220620.pdfneovascular glaucomaetiologypathogenesisdiagnosisiris/angle neovascularizationvascular endothelial growth factor |
spellingShingle | Dan Calugaru Mihai Calugaru Etiology, pathogenesis, and diagnosis of neovascular glaucoma International Journal of Ophthalmology neovascular glaucoma etiology pathogenesis diagnosis iris/angle neovascularization vascular endothelial growth factor |
title | Etiology, pathogenesis, and diagnosis of neovascular glaucoma |
title_full | Etiology, pathogenesis, and diagnosis of neovascular glaucoma |
title_fullStr | Etiology, pathogenesis, and diagnosis of neovascular glaucoma |
title_full_unstemmed | Etiology, pathogenesis, and diagnosis of neovascular glaucoma |
title_short | Etiology, pathogenesis, and diagnosis of neovascular glaucoma |
title_sort | etiology pathogenesis and diagnosis of neovascular glaucoma |
topic | neovascular glaucoma etiology pathogenesis diagnosis iris/angle neovascularization vascular endothelial growth factor |
url | http://ies.ijo.cn/en_publish/2022/6/20220620.pdf |
work_keys_str_mv | AT dancalugaru etiologypathogenesisanddiagnosisofneovascularglaucoma AT mihaicalugaru etiologypathogenesisanddiagnosisofneovascularglaucoma |