Etiology, pathogenesis, and diagnosis of neovascular glaucoma

Neovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glauc...

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Main Authors: Dan Calugaru, Mihai Calugaru
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2022-06-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2022/6/20220620.pdf
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author Dan Calugaru
Mihai Calugaru
author_facet Dan Calugaru
Mihai Calugaru
author_sort Dan Calugaru
collection DOAJ
description Neovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glaucoma are diabetic retinopathy, ischemic central retinal vein occlusion, and ocular ischemic syndrome. Uncommon causes include ocular radiation, ocular tumors, uveitis and other miscellaneous conditions. Vascular endothelial growth factor is an important and likely predominant agent involved in the pathogenesis of intraocular neovascularization and neovascular glaucoma. The evolution of clinical and histopathological changes from predisposing conditions to the occurrence of rubeosis iridis and neovascular glaucoma is divided into four stages: prerubeosis, preglaucoma, open angle glaucoma, and angle-closure glaucoma.
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spelling doaj.art-e0a831956bf4437b8b6c926c640c149b2022-12-22T02:10:22ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982022-06-011561005101010.18240/ijo.2022.06.2020220620Etiology, pathogenesis, and diagnosis of neovascular glaucomaDan Calugaru0Mihai Calugaru1Mihai Călugăru. Strada Brâncoveanu 11, Cluj-Napoca 400467, Romania. mihai.calugaru@mail.dntcj.roDepartment of Ophthalmology, University of Medicine, Cluj-Napoca 400467, RomaniaNeovascular glaucoma is defined as iris and/or anterior chamber angle neovascularization associated with increased intraocular pressure. It is a secondary glaucoma that is most frequently caused by severe retinal ischemia. The most common diseases responsible for the development of neovascular glaucoma are diabetic retinopathy, ischemic central retinal vein occlusion, and ocular ischemic syndrome. Uncommon causes include ocular radiation, ocular tumors, uveitis and other miscellaneous conditions. Vascular endothelial growth factor is an important and likely predominant agent involved in the pathogenesis of intraocular neovascularization and neovascular glaucoma. The evolution of clinical and histopathological changes from predisposing conditions to the occurrence of rubeosis iridis and neovascular glaucoma is divided into four stages: prerubeosis, preglaucoma, open angle glaucoma, and angle-closure glaucoma.http://ies.ijo.cn/en_publish/2022/6/20220620.pdfneovascular glaucomaetiologypathogenesisdiagnosisiris/angle neovascularizationvascular endothelial growth factor
spellingShingle Dan Calugaru
Mihai Calugaru
Etiology, pathogenesis, and diagnosis of neovascular glaucoma
International Journal of Ophthalmology
neovascular glaucoma
etiology
pathogenesis
diagnosis
iris/angle neovascularization
vascular endothelial growth factor
title Etiology, pathogenesis, and diagnosis of neovascular glaucoma
title_full Etiology, pathogenesis, and diagnosis of neovascular glaucoma
title_fullStr Etiology, pathogenesis, and diagnosis of neovascular glaucoma
title_full_unstemmed Etiology, pathogenesis, and diagnosis of neovascular glaucoma
title_short Etiology, pathogenesis, and diagnosis of neovascular glaucoma
title_sort etiology pathogenesis and diagnosis of neovascular glaucoma
topic neovascular glaucoma
etiology
pathogenesis
diagnosis
iris/angle neovascularization
vascular endothelial growth factor
url http://ies.ijo.cn/en_publish/2022/6/20220620.pdf
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