Using Magnetic Nanoparticles for Gene Transfer to Neural Stem Cells: Stem Cell Propagation Method Influences Outcomes

Using Magnetic Nanoparticles for Gene Transfer to Neural Stem Cells: Stem Cell Propagation Method Influences Outcomes

Genetically engineered neural stem cell (NSC) transplants offer a key strategy to augment neural repair by releasing therapeutic biomolecules into injury sites. Genetic modification of NSCs is heavily reliant on viral vectors but cytotoxic effects have prompted development of non-viral alternatives,...

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Bibliographic Details
Main Authors: Mark R. Pickard, Christopher F. Adams, Perrine Barraud, Divya M. Chari
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Journal of Functional Biomaterials
Subjects:
nanoparticle
magnetofection
neural cell
stem cell
transplantation
genetic engineering
Online Access:http://www.mdpi.com/2079-4983/6/2/259

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