Rare case of EBV-induced colitis in an immunocompetent individual

Epstein-Barr virus (EBV) is a member of the herpes virus family and affects people worldwide. EBV-infected colitis can occur in patients in immunocompromised states. However, EBV-induced colitis in immunocompetent patients is extremely rare. A 34-year-old man with a prior history of possible intussu...

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Main Authors: Catherine Choi, Qi Yu, Pratik Q Deb, Weizheng Wang
Format: Article
Language:English
Published: BMJ Publishing Group 2020-12-01
Series:BMJ Open Gastroenterology
Online Access:https://bmjopengastro.bmj.com/content/7/1/e000360.full
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author Catherine Choi
Qi Yu
Pratik Q Deb
Weizheng Wang
author_facet Catherine Choi
Qi Yu
Pratik Q Deb
Weizheng Wang
author_sort Catherine Choi
collection DOAJ
description Epstein-Barr virus (EBV) is a member of the herpes virus family and affects people worldwide. EBV-infected colitis can occur in patients in immunocompromised states. However, EBV-induced colitis in immunocompetent patients is extremely rare. A 34-year-old man with a prior history of possible intussusception, and who underwent a right hemicolectomy, presented with abdominal pain and rectal bleeding. Laboratory investigations were unremarkable, and the patient underwent a colonoscopy, which showed EBV-infected colitis. Both infectious and inflammatory bowel disease (IBD) workups were negative. The patient’s symptoms were resolved with supportive therapy. A repeat colonoscopy showed normal colonic mucosa with an absence of EBV infection. Without evidence of IBD or infectious aetiologies, EBV-associated colitis is a rare finding in an immunocompetent patient.
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spelling doaj.art-e0ab5efb9a8c4f41abf01d27931b88cf2024-12-14T17:05:09ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742020-12-017110.1136/bmjgast-2019-000360Rare case of EBV-induced colitis in an immunocompetent individualCatherine Choi0Qi Yu1Pratik Q Deb2Weizheng Wang3Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USAThe First Affiliated Hospital Of Zhengzhou University, Zhengzhou, ChinaDepartment of Pathology, Immunology & Laboratory Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USAGastroenterology and Hepatology Division, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USAEpstein-Barr virus (EBV) is a member of the herpes virus family and affects people worldwide. EBV-infected colitis can occur in patients in immunocompromised states. However, EBV-induced colitis in immunocompetent patients is extremely rare. A 34-year-old man with a prior history of possible intussusception, and who underwent a right hemicolectomy, presented with abdominal pain and rectal bleeding. Laboratory investigations were unremarkable, and the patient underwent a colonoscopy, which showed EBV-infected colitis. Both infectious and inflammatory bowel disease (IBD) workups were negative. The patient’s symptoms were resolved with supportive therapy. A repeat colonoscopy showed normal colonic mucosa with an absence of EBV infection. Without evidence of IBD or infectious aetiologies, EBV-associated colitis is a rare finding in an immunocompetent patient.https://bmjopengastro.bmj.com/content/7/1/e000360.full
spellingShingle Catherine Choi
Qi Yu
Pratik Q Deb
Weizheng Wang
Rare case of EBV-induced colitis in an immunocompetent individual
BMJ Open Gastroenterology
title Rare case of EBV-induced colitis in an immunocompetent individual
title_full Rare case of EBV-induced colitis in an immunocompetent individual
title_fullStr Rare case of EBV-induced colitis in an immunocompetent individual
title_full_unstemmed Rare case of EBV-induced colitis in an immunocompetent individual
title_short Rare case of EBV-induced colitis in an immunocompetent individual
title_sort rare case of ebv induced colitis in an immunocompetent individual
url https://bmjopengastro.bmj.com/content/7/1/e000360.full
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