Importance of Water Transport in Mammalian Female Reproductive Tract
Aquaporins (AQPs) are involved in water homeostasis in tissues and are ubiquitous in the reproductive tract. AQPs are classified into classical aquaporins (AQP0, 1, 2, 4, 5, 6 and 8), aquaglycerolporins (AQP3, 7, 9, and 10) and superaquaporins (AQP11 and 12). Nine AQPs were described in the mammalia...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-01-01
|
| Series: | Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2306-7381/10/1/50 |
| _version_ | 1827621370021806080 |
|---|---|
| author | Lluis Ferré-Dolcet Maria Montserrat Rivera del Alamo |
| author_facet | Lluis Ferré-Dolcet Maria Montserrat Rivera del Alamo |
| author_sort | Lluis Ferré-Dolcet |
| collection | DOAJ |
| description | Aquaporins (AQPs) are involved in water homeostasis in tissues and are ubiquitous in the reproductive tract. AQPs are classified into classical aquaporins (AQP0, 1, 2, 4, 5, 6 and 8), aquaglycerolporins (AQP3, 7, 9, and 10) and superaquaporins (AQP11 and 12). Nine AQPs were described in the mammalian female reproductive tract. Some of their functions are influenced by sexual steroid hormones. The continuous physiological changes that occur throughout the sexual cycle, pregnancy and parturition, modify the expression of AQPs, thus creating at every moment the required water homeostasis. AQPs in the ovary regulate follicular development and ovulation. In the vagina and the cervix, AQPs are involved mainly in lubrication. In the uterus, AQPs are mostly mediated by estradiol and progesterone to prepare the endometrium for possible embryo implantation and fetal development. In the placenta, AQPs are responsible for the fluid support to the fetus to maintain fetal homeostasis that ensures correct fetal development as pregnancy goes on. This review is focused on understanding the role of AQPs in the mammalian female reproductive tract during the sexual cycle of pregnancy and parturition. |
| first_indexed | 2024-03-09T11:03:39Z |
| format | Article |
| id | doaj.art-e0ac59532a6a468ab5b309800250b3b6 |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-09T11:03:39Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-e0ac59532a6a468ab5b309800250b3b62023-12-01T01:08:23ZengMDPI AGVeterinary Sciences2306-73812023-01-011015010.3390/vetsci10010050Importance of Water Transport in Mammalian Female Reproductive TractLluis Ferré-Dolcet0Maria Montserrat Rivera del Alamo1San Marco Veterinary Clinic and Laboratory, 35030 Veggiano, ItalyDepartament de Medicina i Cirurgia Animals, Veterinary College, Universitat Autònoma de Barcelona, 08913 Bellaterra, SpainAquaporins (AQPs) are involved in water homeostasis in tissues and are ubiquitous in the reproductive tract. AQPs are classified into classical aquaporins (AQP0, 1, 2, 4, 5, 6 and 8), aquaglycerolporins (AQP3, 7, 9, and 10) and superaquaporins (AQP11 and 12). Nine AQPs were described in the mammalian female reproductive tract. Some of their functions are influenced by sexual steroid hormones. The continuous physiological changes that occur throughout the sexual cycle, pregnancy and parturition, modify the expression of AQPs, thus creating at every moment the required water homeostasis. AQPs in the ovary regulate follicular development and ovulation. In the vagina and the cervix, AQPs are involved mainly in lubrication. In the uterus, AQPs are mostly mediated by estradiol and progesterone to prepare the endometrium for possible embryo implantation and fetal development. In the placenta, AQPs are responsible for the fluid support to the fetus to maintain fetal homeostasis that ensures correct fetal development as pregnancy goes on. This review is focused on understanding the role of AQPs in the mammalian female reproductive tract during the sexual cycle of pregnancy and parturition.https://www.mdpi.com/2306-7381/10/1/50aquaporinsfemale reproductive tractreproductionplacentawater homeostasis |
| spellingShingle | Lluis Ferré-Dolcet Maria Montserrat Rivera del Alamo Importance of Water Transport in Mammalian Female Reproductive Tract Veterinary Sciences aquaporins female reproductive tract reproduction placenta water homeostasis |
| title | Importance of Water Transport in Mammalian Female Reproductive Tract |
| title_full | Importance of Water Transport in Mammalian Female Reproductive Tract |
| title_fullStr | Importance of Water Transport in Mammalian Female Reproductive Tract |
| title_full_unstemmed | Importance of Water Transport in Mammalian Female Reproductive Tract |
| title_short | Importance of Water Transport in Mammalian Female Reproductive Tract |
| title_sort | importance of water transport in mammalian female reproductive tract |
| topic | aquaporins female reproductive tract reproduction placenta water homeostasis |
| url | https://www.mdpi.com/2306-7381/10/1/50 |
| work_keys_str_mv | AT lluisferredolcet importanceofwatertransportinmammalianfemalereproductivetract AT mariamontserratriveradelalamo importanceofwatertransportinmammalianfemalereproductivetract |