Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis

Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis

Abstract Background Accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis in clinical specimens and culture isolates to first-line drugs is crucial for diagnosis and management of multidrug-resistant tuberculosis (MDR-TB). Resistance of M. tuberculosis to rifampicin is mainly due...

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Bibliographic Details
Main Authors: Noura M. Al-Mutairi, Suhail Ahmad, Eiman Mokaddas, Hanaa S. Eldeen, Susan Joseph
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Infectious Diseases
Subjects:
Mycobacterium tuberculosis
Polydrug resistance
rpoB disputed mutations
Prevalence
Online Access:http://link.springer.com/article/10.1186/s12879-018-3638-z

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