Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications
This review presents literature data: the history of the discovery of quinoid compounds, their biosynthesis and biological activity. Special attention is paid to the description of the quinoid pigments of the sea urchins <i>Scaphechinus mirabilis</i> (from the family <i>Scutellidae...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/20/10/611 |
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| author | Natalya V. Ageenko Konstantin V. Kiselev Nelly A. Odintsova |
| author_facet | Natalya V. Ageenko Konstantin V. Kiselev Nelly A. Odintsova |
| author_sort | Natalya V. Ageenko |
| collection | DOAJ |
| description | This review presents literature data: the history of the discovery of quinoid compounds, their biosynthesis and biological activity. Special attention is paid to the description of the quinoid pigments of the sea urchins <i>Scaphechinus mirabilis</i> (from the family <i>Scutellidae</i>) and <i>Strongylocentrotus intermedius</i> (from the family <i>Strongylocentrotidae</i>). The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Primary- and some secondary-mouthed animals contain very high concentrations of new biologically active substances, many of which are of significant potential interest for medical purposes. The quinone pigments are products of the secondary metabolism of marine animals, can have complex structures and become the basis for the development of new natural products in echinoids that are modulators of chemical interactions and possible active ingredients in medicinal preparations. More than 5000 chemical compounds with high pharmacological potential have been isolated and described from marine organisms. There are three well known ways of naphthoquinone biosynthesis—polyketide, shikimate and mevalonate. The polyketide pathway is the biosynthesis pathway of various quinones. The shikimate pathway is the main pathway in the biosynthesis of naphthoquinones. It should be noted that all quinoid compounds in plants and animals can be synthesized by various ways of biosynthesis. |
| first_indexed | 2024-03-09T03:35:00Z |
| format | Article |
| id | doaj.art-e0b135ee855840f9b14e8d97e22c333e |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-09T03:35:00Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-e0b135ee855840f9b14e8d97e22c333e2023-12-03T14:51:08ZengMDPI AGMarine Drugs1660-33972022-09-01201061110.3390/md20100611Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential ApplicationsNatalya V. Ageenko0Konstantin V. Kiselev1Nelly A. Odintsova2Laboratory of Cytotechnology, National Scientific Center of Marine Biology, Federal State Budgetary Institution of Science, The Far Eastern Branch of the Russian Academy of Sciences (FEB RAS), 690041 Vladivostok, RussiaLaboratory of Biotechnology, Federal Scientific Center of the East Asia Terrestrial Biodiversity, Federal State Budgetary Institution of Science, FEB RAS, 690022 Vladivostok, RussiaLaboratory of Cytotechnology, National Scientific Center of Marine Biology, Federal State Budgetary Institution of Science, The Far Eastern Branch of the Russian Academy of Sciences (FEB RAS), 690041 Vladivostok, RussiaThis review presents literature data: the history of the discovery of quinoid compounds, their biosynthesis and biological activity. Special attention is paid to the description of the quinoid pigments of the sea urchins <i>Scaphechinus mirabilis</i> (from the family <i>Scutellidae</i>) and <i>Strongylocentrotus intermedius</i> (from the family <i>Strongylocentrotidae</i>). The marine environment is considered one of the most important sources of natural bioactive compounds with extremely rich biodiversity. Primary- and some secondary-mouthed animals contain very high concentrations of new biologically active substances, many of which are of significant potential interest for medical purposes. The quinone pigments are products of the secondary metabolism of marine animals, can have complex structures and become the basis for the development of new natural products in echinoids that are modulators of chemical interactions and possible active ingredients in medicinal preparations. More than 5000 chemical compounds with high pharmacological potential have been isolated and described from marine organisms. There are three well known ways of naphthoquinone biosynthesis—polyketide, shikimate and mevalonate. The polyketide pathway is the biosynthesis pathway of various quinones. The shikimate pathway is the main pathway in the biosynthesis of naphthoquinones. It should be noted that all quinoid compounds in plants and animals can be synthesized by various ways of biosynthesis.https://www.mdpi.com/1660-3397/20/10/611biological active substances (BAS)echinoidsnaphthoquinonessea urchinspigment cells |
| spellingShingle | Natalya V. Ageenko Konstantin V. Kiselev Nelly A. Odintsova Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications Marine Drugs biological active substances (BAS) echinoids naphthoquinones sea urchins pigment cells |
| title | Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications |
| title_full | Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications |
| title_fullStr | Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications |
| title_full_unstemmed | Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications |
| title_short | Quinoid Pigments of Sea Urchins <em>Scaphechinus mirabilis</em> and <em>Strongylocentrotus intermedius</em>: Biological Activity and Potential Applications |
| title_sort | quinoid pigments of sea urchins em scaphechinus mirabilis em and em strongylocentrotus intermedius em biological activity and potential applications |
| topic | biological active substances (BAS) echinoids naphthoquinones sea urchins pigment cells |
| url | https://www.mdpi.com/1660-3397/20/10/611 |
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