Particulate bone matrix usage for alveolar bone conservation
Different filling materials have been used in an attempt to repair bone loss situations. Objective: The present study aimed to examine the effect of a bone matrix in post-extraction remodelling of the alveolar bone, and to perform a histomorphometric analysis of the residual alveolar ridges in Wista...
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| Format: | Article |
| Language: | English |
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Universidad Nacional de Córdoba
2013-09-01
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| Series: | Revista de la Facultad de Ciencias Médicas de Córdoba |
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| Online Access: | https://revistas.unc.edu.ar/index.php/med/article/view/20186 |
| _version_ | 1819280374734258176 |
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| author | Sebastián Fontana Luis Plavnik Miguel Filippetti Alicia Inés Malberti |
| author_facet | Sebastián Fontana Luis Plavnik Miguel Filippetti Alicia Inés Malberti |
| author_sort | Sebastián Fontana |
| collection | DOAJ |
| description | Different filling materials have been used in an attempt to repair bone loss situations. Objective: The present study aimed to examine the effect of a bone matrix in post-extraction remodelling of the alveolar bone, and to perform a histomorphometric analysis of the residual alveolar ridges in Wistar rats.
Material and Methods: Both rat first lower molars were extracted and the right alveoli were filled with particles of a bone matrix with mineral components (MO-UNC) (experimental group, EG). The left alveoli were used as a control group (CG). The animals were sacrificed at 0 hrs, 15, 30 and 60 days after extraction, and the samples were processed. Histological sections were made at the level of the mesial alveolus of the first lower molar.
Repair of the alveoli was histologically evaluated and a histomorphometric study of total alveolar volume (TAV), height of the buccal plate (Bh), height of the lingual plate (Lh) and percentage of osseointegration (OI) of the particles was performed to compare the residual ridges of CG with those of the EG. Statistical analysis of the data was performed.
Results: In the cases of the experimental group, newly-formed bone tissue was identified around the MO-UNC particles (osseointegration). Histomorphometric data indicate that, at 60 days post-extraction, TAV was significantly greater for EG when compared with CG (p<0.05) and the percentage of osseointegration of the particles increased as a function of time (57.6 %, 90.5% y 95.5%, for EG at 15, 30 y 60 days respectively). Conclusions: The bone matrix (MO-UNC) evaluated in this study is an osteoconductive material that prevents the collapse of post-extraction alveolar bone. |
| first_indexed | 2024-12-24T00:42:47Z |
| format | Article |
| id | doaj.art-e0b1dbe8de904b7c933abc0e3ca9c2df |
| institution | Directory Open Access Journal |
| issn | 0014-6722 1853-0605 |
| language | English |
| last_indexed | 2024-12-24T00:42:47Z |
| publishDate | 2013-09-01 |
| publisher | Universidad Nacional de Córdoba |
| record_format | Article |
| series | Revista de la Facultad de Ciencias Médicas de Córdoba |
| spelling | doaj.art-e0b1dbe8de904b7c933abc0e3ca9c2df2022-12-21T17:23:55ZengUniversidad Nacional de CórdobaRevista de la Facultad de Ciencias Médicas de Córdoba0014-67221853-06052013-09-0170310.31053/1853.0605.v70.n3.20186Particulate bone matrix usage for alveolar bone conservationSebastián Fontana0Luis Plavnik1Miguel Filippetti2Alicia Inés Malberti3Chair of Histology. Dentistry Faculty. National University of Córdoba.Science and Technology Area. CREO Foundation.Human Tissue Processing Plant. UNC-Biotecnia. National University of CórdobaCátedra de Histología. Departamento de Biología Oral, Facultad de Odontología. Universidad Nacional de Córdoba.Different filling materials have been used in an attempt to repair bone loss situations. Objective: The present study aimed to examine the effect of a bone matrix in post-extraction remodelling of the alveolar bone, and to perform a histomorphometric analysis of the residual alveolar ridges in Wistar rats. Material and Methods: Both rat first lower molars were extracted and the right alveoli were filled with particles of a bone matrix with mineral components (MO-UNC) (experimental group, EG). The left alveoli were used as a control group (CG). The animals were sacrificed at 0 hrs, 15, 30 and 60 days after extraction, and the samples were processed. Histological sections were made at the level of the mesial alveolus of the first lower molar. Repair of the alveoli was histologically evaluated and a histomorphometric study of total alveolar volume (TAV), height of the buccal plate (Bh), height of the lingual plate (Lh) and percentage of osseointegration (OI) of the particles was performed to compare the residual ridges of CG with those of the EG. Statistical analysis of the data was performed. Results: In the cases of the experimental group, newly-formed bone tissue was identified around the MO-UNC particles (osseointegration). Histomorphometric data indicate that, at 60 days post-extraction, TAV was significantly greater for EG when compared with CG (p<0.05) and the percentage of osseointegration of the particles increased as a function of time (57.6 %, 90.5% y 95.5%, for EG at 15, 30 y 60 days respectively). Conclusions: The bone matrix (MO-UNC) evaluated in this study is an osteoconductive material that prevents the collapse of post-extraction alveolar bone.https://revistas.unc.edu.ar/index.php/med/article/view/20186bone transplantationalveolar ridges preservationpost-extraction alveoliosteoconductive materials |
| spellingShingle | Sebastián Fontana Luis Plavnik Miguel Filippetti Alicia Inés Malberti Particulate bone matrix usage for alveolar bone conservation Revista de la Facultad de Ciencias Médicas de Córdoba bone transplantation alveolar ridges preservation post-extraction alveoli osteoconductive materials |
| title | Particulate bone matrix usage for alveolar bone conservation |
| title_full | Particulate bone matrix usage for alveolar bone conservation |
| title_fullStr | Particulate bone matrix usage for alveolar bone conservation |
| title_full_unstemmed | Particulate bone matrix usage for alveolar bone conservation |
| title_short | Particulate bone matrix usage for alveolar bone conservation |
| title_sort | particulate bone matrix usage for alveolar bone conservation |
| topic | bone transplantation alveolar ridges preservation post-extraction alveoli osteoconductive materials |
| url | https://revistas.unc.edu.ar/index.php/med/article/view/20186 |
| work_keys_str_mv | AT sebastianfontana particulatebonematrixusageforalveolarboneconservation AT luisplavnik particulatebonematrixusageforalveolarboneconservation AT miguelfilippetti particulatebonematrixusageforalveolarboneconservation AT aliciainesmalberti particulatebonematrixusageforalveolarboneconservation |