Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran
Antibiotic guidelines have proven to be a simple and effective intervention to guide the choice of appropriate empiric antibiotic regimens. The goals of this study were to evaluate adherence to guidelines and streamlining of antibiotics. Hospital records of hospitalized patients in infectious diseas...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-01-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3858 |
| _version_ | 1828746257989894144 |
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| author | Hossein Khalili Sepideh Elyasi Shima Hatamkhani Simin Dashti-Khavidaki |
| author_facet | Hossein Khalili Sepideh Elyasi Shima Hatamkhani Simin Dashti-Khavidaki |
| author_sort | Hossein Khalili |
| collection | DOAJ |
| description | Antibiotic guidelines have proven to be a simple and effective intervention to guide the choice of appropriate empiric antibiotic regimens. The goals of this study were to evaluate adherence to guidelines and streamlining of antibiotics. Hospital records of hospitalized patients in infectious diseases ward Imam Khomeini Hospital, Tehran, Iran, from May 2008 to September 2009 were reviewed. Adherence to guideline was defined as the use of empiric antibiotic in accordance with the clinical diagnosis and local guideline recommendations. In this study, 528 patients with a confirmed infectious disease diagnosis were considered for analysis. The four most frequent diagnoses were skin and soft tissue infections, tuberculosis, respiratory tract infections, and HIV associated opportunistic infections. The most frequent prescribed antibiotic was ceftriaxone. Overall adherence to guideline was 70.8% and the adherence for the most frequent diagnosis was 68%. Frequency of compatibility with the guidelines for were administrated regimes on the basis of drug selection, dosage form and drug dosing were 86.2%, 97% and 84.7%, respectively. The mean lag time between patients' hospital admission and starting empiric therapy was 1.69±4.9 days. In general, physicians' adherence with guidelines for empiric antibiotic therapy was high in infectious disease ward with a justified delay. Larger studies are required to establish these conclusions. |
| first_indexed | 2024-04-14T04:21:15Z |
| format | Article |
| id | doaj.art-e0b296c63b9b42bf9fc1653a7b2ae275 |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-14T04:21:15Z |
| publishDate | 2012-01-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-e0b296c63b9b42bf9fc1653a7b2ae2752022-12-22T02:12:32ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942012-01-01501Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, IranHossein Khalili0Sepideh Elyasi1Shima Hatamkhani2Simin Dashti-Khavidaki3Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.Antibiotic guidelines have proven to be a simple and effective intervention to guide the choice of appropriate empiric antibiotic regimens. The goals of this study were to evaluate adherence to guidelines and streamlining of antibiotics. Hospital records of hospitalized patients in infectious diseases ward Imam Khomeini Hospital, Tehran, Iran, from May 2008 to September 2009 were reviewed. Adherence to guideline was defined as the use of empiric antibiotic in accordance with the clinical diagnosis and local guideline recommendations. In this study, 528 patients with a confirmed infectious disease diagnosis were considered for analysis. The four most frequent diagnoses were skin and soft tissue infections, tuberculosis, respiratory tract infections, and HIV associated opportunistic infections. The most frequent prescribed antibiotic was ceftriaxone. Overall adherence to guideline was 70.8% and the adherence for the most frequent diagnosis was 68%. Frequency of compatibility with the guidelines for were administrated regimes on the basis of drug selection, dosage form and drug dosing were 86.2%, 97% and 84.7%, respectively. The mean lag time between patients' hospital admission and starting empiric therapy was 1.69±4.9 days. In general, physicians' adherence with guidelines for empiric antibiotic therapy was high in infectious disease ward with a justified delay. Larger studies are required to establish these conclusions.https://acta.tums.ac.ir/index.php/acta/article/view/3858Anti-bacterial agentsGuidelineAdherenceguideline |
| spellingShingle | Hossein Khalili Sepideh Elyasi Shima Hatamkhani Simin Dashti-Khavidaki Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran Acta Medica Iranica Anti-bacterial agents Guideline Adherence guideline |
| title | Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran |
| title_full | Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran |
| title_fullStr | Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran |
| title_full_unstemmed | Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran |
| title_short | Adherence to Empiric Antibiotic Therapy Guideline in a Referral Teaching Hospital, Tehran, Iran |
| title_sort | adherence to empiric antibiotic therapy guideline in a referral teaching hospital tehran iran |
| topic | Anti-bacterial agents Guideline Adherence guideline |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3858 |
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