A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis
Polymyositis is a rare condition with an unknown etiology occurring more frequently in adult women. There is a lack of evidence on the coexistence of PM and CMV infection in a patient with hypothyroidism due to Hashimoto’s Thyroiditis. However, the growing occurrence of both CMV infection and the si...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-12-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/13/12/2331 |
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| author | Ergeta Ktona Blerta Budani Ioannis Kostas-Agnantis Alma Idrizi |
| author_facet | Ergeta Ktona Blerta Budani Ioannis Kostas-Agnantis Alma Idrizi |
| author_sort | Ergeta Ktona |
| collection | DOAJ |
| description | Polymyositis is a rare condition with an unknown etiology occurring more frequently in adult women. There is a lack of evidence on the coexistence of PM and CMV infection in a patient with hypothyroidism due to Hashimoto’s Thyroiditis. However, the growing occurrence of both CMV infection and the simultaneous occurrence of autoimmune diseases points out a relationship, while the association direction remains unclear. Case outline: A 32-year-old woman recently treated for HT hypothyroidism was admitted to the hospital two weeks after being treated for common flu by the family doctor, complaining about a worsening condition with muscle pain, weakness, frequent falls, and fatigue. The first tests showed a normalized thyroid function, with elevated values of troponin and serum creatinine kinase (CK). The immunological tests revealed the presence of a high titer of CMV IgG antibodies and raised levels of CMV DNA. Pelvis MRI images demonstrated markedly elevated signals on the STIR sequences in the pelvis, thighs, and calves, indicating active and severe multifocal myositis. The diagnosis of PM was confirmed with the muscle biopsy on day 7 of hospitalization. The patient showed significant improvements within two weeks after the medical therapy and physiotherapy. |
| first_indexed | 2024-03-08T20:36:17Z |
| format | Article |
| id | doaj.art-e0b37ea636974ab2b9bbff38e72d21eb |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-08T20:36:17Z |
| publishDate | 2023-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-e0b37ea636974ab2b9bbff38e72d21eb2023-12-22T14:21:20ZengMDPI AGLife2075-17292023-12-011312233110.3390/life13122331A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s ThyroiditisErgeta Ktona0Blerta Budani1Ioannis Kostas-Agnantis2Alma Idrizi3Rheumatology Department, University Hospital Center, 1001 Tirana, AlbaniaFaculty of Technical Medical Sciences, University of Elbasan, 3001 Elbasan, AlbaniaOrthopaedic Department, University Hospital of Ioannina, 451 10 Ioannina, GreeceNephrology Department, University Hospital Center, 1001 Tirana, AlbaniaPolymyositis is a rare condition with an unknown etiology occurring more frequently in adult women. There is a lack of evidence on the coexistence of PM and CMV infection in a patient with hypothyroidism due to Hashimoto’s Thyroiditis. However, the growing occurrence of both CMV infection and the simultaneous occurrence of autoimmune diseases points out a relationship, while the association direction remains unclear. Case outline: A 32-year-old woman recently treated for HT hypothyroidism was admitted to the hospital two weeks after being treated for common flu by the family doctor, complaining about a worsening condition with muscle pain, weakness, frequent falls, and fatigue. The first tests showed a normalized thyroid function, with elevated values of troponin and serum creatinine kinase (CK). The immunological tests revealed the presence of a high titer of CMV IgG antibodies and raised levels of CMV DNA. Pelvis MRI images demonstrated markedly elevated signals on the STIR sequences in the pelvis, thighs, and calves, indicating active and severe multifocal myositis. The diagnosis of PM was confirmed with the muscle biopsy on day 7 of hospitalization. The patient showed significant improvements within two weeks after the medical therapy and physiotherapy.https://www.mdpi.com/2075-1729/13/12/2331polymyositiscytomegalovirus infectionhashimoto’s thyroiditisassociationcoexistenceautoimmune diseases |
| spellingShingle | Ergeta Ktona Blerta Budani Ioannis Kostas-Agnantis Alma Idrizi A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis Life polymyositis cytomegalovirus infection hashimoto’s thyroiditis association coexistence autoimmune diseases |
| title | A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis |
| title_full | A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis |
| title_fullStr | A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis |
| title_full_unstemmed | A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis |
| title_short | A Case of Polymyositis Associated with Cytomegalovirus Infection in a Patient with Hashimoto’s Thyroiditis |
| title_sort | case of polymyositis associated with cytomegalovirus infection in a patient with hashimoto s thyroiditis |
| topic | polymyositis cytomegalovirus infection hashimoto’s thyroiditis association coexistence autoimmune diseases |
| url | https://www.mdpi.com/2075-1729/13/12/2331 |
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