Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics
ABSTRACTThe present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, α-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabo...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | CyTA - Journal of Food |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19476337.2023.2284330 |
| _version_ | 1797392496969383936 |
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| author | Papichaya Netrprachit Nitra Nuangchamnong Nurul Shazini Ramli Maulidiani Maulidiani Ahmed Mediani Nur Khaleeda Zulaikha Zolkeflee Sudarat Jiamyangyuen Faridah Abas |
| author_facet | Papichaya Netrprachit Nitra Nuangchamnong Nurul Shazini Ramli Maulidiani Maulidiani Ahmed Mediani Nur Khaleeda Zulaikha Zolkeflee Sudarat Jiamyangyuen Faridah Abas |
| author_sort | Papichaya Netrprachit |
| collection | DOAJ |
| description | ABSTRACTThe present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, α-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabolites by using the 1H NMR-based metabolomics approach. The methanol extract of RR had the highest DPPH scavenging and α-glucosidase inhibitory activities. The water extracts of PR and RR exhibited the highest NO inhibitory activity with IC50 values of 176.28 ± 18.78 and 160.69 ± 14.83 µg/mL, respectively. The metabolites that contribute to radical scavenging and α-glucosidase inhibitory activities of RR methanol extract were chlorogenic acid, protocatechuic acid, and tyrosine, whereas nicotinic acid, γ-aminobutyric acid, and citric acid were the metabolites that contributed to the NO inhibitory activity of RR water extract. The RR extracts are potential sources of bioactive compounds with antioxidant and NO inhibitory properties. |
| first_indexed | 2024-03-08T23:48:15Z |
| format | Article |
| id | doaj.art-e0b7b58c2eca4a26b99068766dd7063c |
| institution | Directory Open Access Journal |
| issn | 1947-6337 1947-6345 |
| language | English |
| last_indexed | 2024-03-08T23:48:15Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | CyTA - Journal of Food |
| spelling | doaj.art-e0b7b58c2eca4a26b99068766dd7063c2023-12-13T14:31:47ZengTaylor & Francis GroupCyTA - Journal of Food1947-63371947-63452023-12-0121176077010.1080/19476337.2023.2284330Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomicsPapichaya Netrprachit0Nitra Nuangchamnong1Nurul Shazini Ramli2Maulidiani Maulidiani3Ahmed Mediani4Nur Khaleeda Zulaikha Zolkeflee5Sudarat Jiamyangyuen6Faridah Abas7Department of Agro-industry, Faculty of Agriculture, Natural resources and Environment, Naresuan University, Muang, Phitsanulok, ThailandScience Laboratory Centre, Faculty of Science, Naresuan University, Muang, Phitsanulok, ThailandDepartment of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaFaculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Nerus, Terengganu, MalaysiaMetabolomics Research Laboratory, Institute of Systems Biology (INBIOSIS), Universiti Kebangsaan Malaysia, Bangi, MalaysiaNatural Medicines and Products Research Laboratory, Institute of Bioscience, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaDepartment of Agro-industry, Faculty of Agriculture, Natural resources and Environment, Naresuan University, Muang, Phitsanulok, ThailandDepartment of Food Science, Faculty of Food Science and Technology, Universiti Putra Malaysia, Serdang, Selangor, MalaysiaABSTRACTThe present study determined total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, α-glucosidase, and nitric oxide (NO) inhibitory activities of black (BR), purple (PR), and red rice (RR) extracted with different polarity solvents and characterized the metabolites by using the 1H NMR-based metabolomics approach. The methanol extract of RR had the highest DPPH scavenging and α-glucosidase inhibitory activities. The water extracts of PR and RR exhibited the highest NO inhibitory activity with IC50 values of 176.28 ± 18.78 and 160.69 ± 14.83 µg/mL, respectively. The metabolites that contribute to radical scavenging and α-glucosidase inhibitory activities of RR methanol extract were chlorogenic acid, protocatechuic acid, and tyrosine, whereas nicotinic acid, γ-aminobutyric acid, and citric acid were the metabolites that contributed to the NO inhibitory activity of RR water extract. The RR extracts are potential sources of bioactive compounds with antioxidant and NO inhibitory properties.https://www.tandfonline.com/doi/10.1080/19476337.2023.2284330Pigmented riceantioxidant activityα-glucosidase inhibitory activitynitric oxide inhibition1H-NMR metabolomicsmetabolite profiling |
| spellingShingle | Papichaya Netrprachit Nitra Nuangchamnong Nurul Shazini Ramli Maulidiani Maulidiani Ahmed Mediani Nur Khaleeda Zulaikha Zolkeflee Sudarat Jiamyangyuen Faridah Abas Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics CyTA - Journal of Food Pigmented rice antioxidant activity α-glucosidase inhibitory activity nitric oxide inhibition 1H-NMR metabolomics metabolite profiling |
| title | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_full | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_fullStr | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_full_unstemmed | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_short | Bioactive compounds of pigmented rice extracts reveal by NMR-based metabolomics |
| title_sort | bioactive compounds of pigmented rice extracts reveal by nmr based metabolomics |
| topic | Pigmented rice antioxidant activity α-glucosidase inhibitory activity nitric oxide inhibition 1H-NMR metabolomics metabolite profiling |
| url | https://www.tandfonline.com/doi/10.1080/19476337.2023.2284330 |
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