Lipschütz Ulcer and SARS-CoV-2: What We Currently Know?
Background: In recent years, several interesting case reports have been published which describe the possible role of SARS-CoV-2 infection or vaccination in the etiopathogenesis of Lipschütz ulcer. Our aim is to analyze this association and provide a rapid algorithm that is of support to gynecologis...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Diseases |
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| Online Access: | https://www.mdpi.com/2079-9721/11/3/121 |
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| author | Lucia Merlino Agnese Immacolata Volpicelli Mattia Dominoni Marianna Francesca Pasquali Giulia D’Ovidio Barbara Gardella Roberto Senatori |
| author_facet | Lucia Merlino Agnese Immacolata Volpicelli Mattia Dominoni Marianna Francesca Pasquali Giulia D’Ovidio Barbara Gardella Roberto Senatori |
| author_sort | Lucia Merlino |
| collection | DOAJ |
| description | Background: In recent years, several interesting case reports have been published which describe the possible role of SARS-CoV-2 infection or vaccination in the etiopathogenesis of Lipschütz ulcer. Our aim is to analyze this association and provide a rapid algorithm that is of support to gynecologists and dermatologists both in the diagnosis and in setting up the therapy. To do so, in this paper, we describe an interesting case of acute vulvar ulcer triggered by SARS-CoV-2 infection and review the related literature. Methods: We conducted a literature review including papers published between October 2021 and April 2023, and we described the case of a patient referred to our clinic with Lipschütz ulcer and SARS-CoV-2 infection. Results: In almost all cases analyzed, a correlation with SARS-CoV-2 infection or vaccination was found; ulcers usually manifest after 2 to 4 weeks and are associated with flu-like symptoms. A concordance in review papers, as well as in our case report, was also found about the treatment, which is mainly symptomatic. Conclusions: Previous infection or vaccination for SARS-CoV-2 should be included as possible etiopathogenetic factors in the onset of Lipschütz ulcer. |
| first_indexed | 2024-03-10T22:52:37Z |
| format | Article |
| id | doaj.art-e0b82f72dbc1404d9979de9619bbc1ef |
| institution | Directory Open Access Journal |
| issn | 2079-9721 |
| language | English |
| last_indexed | 2024-03-10T22:52:37Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj.art-e0b82f72dbc1404d9979de9619bbc1ef2023-11-19T10:15:33ZengMDPI AGDiseases2079-97212023-09-0111312110.3390/diseases11030121Lipschütz Ulcer and SARS-CoV-2: What We Currently Know?Lucia Merlino0Agnese Immacolata Volpicelli1Mattia Dominoni2Marianna Francesca Pasquali3Giulia D’Ovidio4Barbara Gardella5Roberto Senatori6Department of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, ItalyDepartment of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, ItalyDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, ItalyDepartment of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, ItalyDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, ItalyItalian Society of Colposcopy and Cervicovaginal Pathology (SICPV), 00186 Rome, ItalyBackground: In recent years, several interesting case reports have been published which describe the possible role of SARS-CoV-2 infection or vaccination in the etiopathogenesis of Lipschütz ulcer. Our aim is to analyze this association and provide a rapid algorithm that is of support to gynecologists and dermatologists both in the diagnosis and in setting up the therapy. To do so, in this paper, we describe an interesting case of acute vulvar ulcer triggered by SARS-CoV-2 infection and review the related literature. Methods: We conducted a literature review including papers published between October 2021 and April 2023, and we described the case of a patient referred to our clinic with Lipschütz ulcer and SARS-CoV-2 infection. Results: In almost all cases analyzed, a correlation with SARS-CoV-2 infection or vaccination was found; ulcers usually manifest after 2 to 4 weeks and are associated with flu-like symptoms. A concordance in review papers, as well as in our case report, was also found about the treatment, which is mainly symptomatic. Conclusions: Previous infection or vaccination for SARS-CoV-2 should be included as possible etiopathogenetic factors in the onset of Lipschütz ulcer.https://www.mdpi.com/2079-9721/11/3/121Lipschütz ulceracute vulvar ulcernon-sexually transmitted vulvar aphthosisSARS-CoV-2COVID-19 |
| spellingShingle | Lucia Merlino Agnese Immacolata Volpicelli Mattia Dominoni Marianna Francesca Pasquali Giulia D’Ovidio Barbara Gardella Roberto Senatori Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? Diseases Lipschütz ulcer acute vulvar ulcer non-sexually transmitted vulvar aphthosis SARS-CoV-2 COVID-19 |
| title | Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? |
| title_full | Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? |
| title_fullStr | Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? |
| title_full_unstemmed | Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? |
| title_short | Lipschütz Ulcer and SARS-CoV-2: What We Currently Know? |
| title_sort | lipschutz ulcer and sars cov 2 what we currently know |
| topic | Lipschütz ulcer acute vulvar ulcer non-sexually transmitted vulvar aphthosis SARS-CoV-2 COVID-19 |
| url | https://www.mdpi.com/2079-9721/11/3/121 |
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