Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro

In this study we investigated the influence of low dosage X - ray irradiation on the incidence of chromosomal damage and changes in mitotic index (MI) in cultured peripheral lymphocytes of the Bosnian and Herzegovinian mountain horse following in vitro irradiation. X-ray irradiation induced a dose-d...

Full description

Bibliographic Details
Main Authors: Rukavina Dunja, Hasanbašić Danica, Suljkanović Edin, Katica Amela
Format: Article
Language:English
Published: Faculty of Veterinary Medicine, Belgrade 2009-01-01
Series:Veterinarski Glasnik
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0350-2457/2009/0350-24570906341R.pdf
_version_ 1818322059538726912
author Rukavina Dunja
Hasanbašić Danica
Suljkanović Edin
Katica Amela
author_facet Rukavina Dunja
Hasanbašić Danica
Suljkanović Edin
Katica Amela
author_sort Rukavina Dunja
collection DOAJ
description In this study we investigated the influence of low dosage X - ray irradiation on the incidence of chromosomal damage and changes in mitotic index (MI) in cultured peripheral lymphocytes of the Bosnian and Herzegovinian mountain horse following in vitro irradiation. X-ray irradiation induced a dose-dependent decrease in MI but only the dose of 0.5 Gy induced a significant decrease (p<0.05) in comparison with the control and other dose groups. The analysis of chromosomal damage revealed a clear dose-dependent increase in the incidence of chromosomal damage per metaphase. Significant differences (p<0.05) were detected by analysis of variance and the LSD test confirmed significant differences between cells that received 0.2 Gy and 0.5 Gy when compared to the control cells and cells that received 0.1 Gy. However, Scheeffes' test assigned significance only to the differences established between the cells that received 0.5 Gy and the other groups of lymphocytes. .
first_indexed 2024-12-13T10:50:47Z
format Article
id doaj.art-e0bc7691f5524fcbabde980f68b5cd3a
institution Directory Open Access Journal
issn 0350-2457
2406-0771
language English
last_indexed 2024-12-13T10:50:47Z
publishDate 2009-01-01
publisher Faculty of Veterinary Medicine, Belgrade
record_format Article
series Veterinarski Glasnik
spelling doaj.art-e0bc7691f5524fcbabde980f68b5cd3a2022-12-21T23:49:51ZengFaculty of Veterinary Medicine, BelgradeVeterinarski Glasnik0350-24572406-07712009-01-01635-634135210.2298/VETGL0906341R0350-24570906341RChromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitroRukavina Dunja0Hasanbašić Danica1Suljkanović Edin2Katica Amela3Veterinarski fakultet, Katedra za biologiju, Sarajevo, Bosna i Hercegovina%SR91-05istaVeterinarska stanica, Srebrenik, Bosna i Hercegovina%SR91-05Veterinarski fakultet, Katedra za histologiju sa embriologijom, Sarajevo, Bosna i Hercegovina%SR91-05In this study we investigated the influence of low dosage X - ray irradiation on the incidence of chromosomal damage and changes in mitotic index (MI) in cultured peripheral lymphocytes of the Bosnian and Herzegovinian mountain horse following in vitro irradiation. X-ray irradiation induced a dose-dependent decrease in MI but only the dose of 0.5 Gy induced a significant decrease (p<0.05) in comparison with the control and other dose groups. The analysis of chromosomal damage revealed a clear dose-dependent increase in the incidence of chromosomal damage per metaphase. Significant differences (p<0.05) were detected by analysis of variance and the LSD test confirmed significant differences between cells that received 0.2 Gy and 0.5 Gy when compared to the control cells and cells that received 0.1 Gy. However, Scheeffes' test assigned significance only to the differences established between the cells that received 0.5 Gy and the other groups of lymphocytes. .http://www.doiserbia.nb.rs/img/doi/0350-2457/2009/0350-24570906341R.pdfchromosomal damagecytogenetic dosimetryhorseionizing irradiation
spellingShingle Rukavina Dunja
Hasanbašić Danica
Suljkanović Edin
Katica Amela
Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
Veterinarski Glasnik
chromosomal damage
cytogenetic dosimetry
horse
ionizing irradiation
title Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
title_full Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
title_fullStr Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
title_full_unstemmed Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
title_short Chromosomal damage and mitotic index in Bosnian and Herzegovinian mountain horse lymphocytes following low dosage X-ray irradiation in vitro
title_sort chromosomal damage and mitotic index in bosnian and herzegovinian mountain horse lymphocytes following low dosage x ray irradiation in vitro
topic chromosomal damage
cytogenetic dosimetry
horse
ionizing irradiation
url http://www.doiserbia.nb.rs/img/doi/0350-2457/2009/0350-24570906341R.pdf
work_keys_str_mv AT rukavinadunja chromosomaldamageandmitoticindexinbosnianandherzegovinianmountainhorselymphocytesfollowinglowdosagexrayirradiationinvitro
AT hasanbasicdanica chromosomaldamageandmitoticindexinbosnianandherzegovinianmountainhorselymphocytesfollowinglowdosagexrayirradiationinvitro
AT suljkanovicedin chromosomaldamageandmitoticindexinbosnianandherzegovinianmountainhorselymphocytesfollowinglowdosagexrayirradiationinvitro
AT katicaamela chromosomaldamageandmitoticindexinbosnianandherzegovinianmountainhorselymphocytesfollowinglowdosagexrayirradiationinvitro