The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.

The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey.

A functional single nucleotide polymorphism (SNP) of the PTPN22 gene encoding a protein tyrosine phosphatase has been associated with autoimmune disorders including myasthenia gravis (MG). As the PTPN22 R620W polymorphism has a wide variation of allele frequencies among different populations, this p...

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Main Authors: Gizem A Kaya, Ayse N Coşkun, Vuslat Yılmaz, Piraye Oflazer, Yeşim Gülsen-Parman, Fikret Aysal, Rian Disci, Haner Direskeneli, Alexander Marx, Feza Deymeer, Güher Saruhan-Direskeneli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4132102?pdf=render

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