May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database
The ICI–RS has proposed the definition of COUB (Coexistent Overactive-Underactive Bladder) as a syndrome characterized by voiding and filling LUTS in the same patient. The aim of this study is to explore whether the presence of DO can lead to DU, because of muscle asthenia and fatigue of the smooth...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Continence |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772973723009190 |
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| author | Eleonora Rosato Livia Mollo Vincenza Laurendi Luca Orecchia Pietro Bachetti Enrico Finazzi Agrò |
| author_facet | Eleonora Rosato Livia Mollo Vincenza Laurendi Luca Orecchia Pietro Bachetti Enrico Finazzi Agrò |
| author_sort | Eleonora Rosato |
| collection | DOAJ |
| description | The ICI–RS has proposed the definition of COUB (Coexistent Overactive-Underactive Bladder) as a syndrome characterized by voiding and filling LUTS in the same patient. The aim of this study is to explore whether the presence of DO can lead to DU, because of muscle asthenia and fatigue of the smooth muscle cells.Retrospectively, we included all consecutive male patients with LUTS who underwent an invasive UDS (January 2011–December 2022). Patients with neurologic diseases or with previous LUT surgery were excluded. They were divided into normal detrusor function, Group A and Detrusor Overactivity, Group B during the filling phase. BOOI, BCI, PVR and BVE were compared in the two groups. DO patients were divided according to the phasic or terminal DO contractions and mean BCI was calculated in these subgroups.We analysed 425 male patients with LUTS. During filling phase, 167 patients (39.3%, Group A) showed NDF and 258 patients (60.7% Group B) DO. 207 of them (80.2%) had phasic detrusor contractions and 51 (20.8%) had terminal DO. MCC was 409.8 mL and 308.7 mL (p<0.0001), respectively. During the voiding phase, 176 patients (41.4) were obstructed, 100 (23.5%) were equivocal and 149 (35.1%) were not obstructed. 179 patients had a BCI ≤100 and 246 (57.9%) >100. 207 (80.2%) patients of the group B showed phasic, while 51 (19.8%) terminal DO; in these subgroups, mean BCI was 118.8 and 112.0 respectively (p 0.806658). |
| first_indexed | 2024-04-24T20:25:20Z |
| format | Article |
| id | doaj.art-e0bd0b11156041adae37281328325aa7 |
| institution | Directory Open Access Journal |
| issn | 2772-9737 |
| language | English |
| last_indexed | 2024-04-24T20:25:20Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Continence |
| spelling | doaj.art-e0bd0b11156041adae37281328325aa72024-03-22T05:41:20ZengElsevierContinence2772-97372024-03-019101061May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic databaseEleonora Rosato0Livia Mollo1Vincenza Laurendi2Luca Orecchia3Pietro Bachetti4Enrico Finazzi Agrò5Correspondence to: Unit of Urology, Fondazione PTV Policlinico Tor Vergata, Italy.; Department of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyDepartment of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyDepartment of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyDepartment of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyDepartment of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyDepartment of Surgical Sciences, Unit of Urology, University of Rome Tor Vergata, Rome, ItalyThe ICI–RS has proposed the definition of COUB (Coexistent Overactive-Underactive Bladder) as a syndrome characterized by voiding and filling LUTS in the same patient. The aim of this study is to explore whether the presence of DO can lead to DU, because of muscle asthenia and fatigue of the smooth muscle cells.Retrospectively, we included all consecutive male patients with LUTS who underwent an invasive UDS (January 2011–December 2022). Patients with neurologic diseases or with previous LUT surgery were excluded. They were divided into normal detrusor function, Group A and Detrusor Overactivity, Group B during the filling phase. BOOI, BCI, PVR and BVE were compared in the two groups. DO patients were divided according to the phasic or terminal DO contractions and mean BCI was calculated in these subgroups.We analysed 425 male patients with LUTS. During filling phase, 167 patients (39.3%, Group A) showed NDF and 258 patients (60.7% Group B) DO. 207 of them (80.2%) had phasic detrusor contractions and 51 (20.8%) had terminal DO. MCC was 409.8 mL and 308.7 mL (p<0.0001), respectively. During the voiding phase, 176 patients (41.4) were obstructed, 100 (23.5%) were equivocal and 149 (35.1%) were not obstructed. 179 patients had a BCI ≤100 and 246 (57.9%) >100. 207 (80.2%) patients of the group B showed phasic, while 51 (19.8%) terminal DO; in these subgroups, mean BCI was 118.8 and 112.0 respectively (p 0.806658).http://www.sciencedirect.com/science/article/pii/S2772973723009190Urodynamic testOveractive bladderUnderactive bladderBladder contractility indexStorage symptomsVoiding symptoms |
| spellingShingle | Eleonora Rosato Livia Mollo Vincenza Laurendi Luca Orecchia Pietro Bachetti Enrico Finazzi Agrò May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database Continence Urodynamic test Overactive bladder Underactive bladder Bladder contractility index Storage symptoms Voiding symptoms |
| title | May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database |
| title_full | May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database |
| title_fullStr | May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database |
| title_full_unstemmed | May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database |
| title_short | May coexisting overactive-underactive bladder (COUB) be due to muscle fatigue? Data from a single-centre urodynamic database |
| title_sort | may coexisting overactive underactive bladder coub be due to muscle fatigue data from a single centre urodynamic database |
| topic | Urodynamic test Overactive bladder Underactive bladder Bladder contractility index Storage symptoms Voiding symptoms |
| url | http://www.sciencedirect.com/science/article/pii/S2772973723009190 |
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