Increased natriuretic peptides not associated with heart failure
Natriuretic peptides (NPs) are key diagnostic and prognostic biomarkers for patients with heart failure (HF). The main mechanism for increasing serum NP levels, which is characteristic of heart failure, is secretion in response to myocardial wall distention. At the same time, according to Russian an...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2021-01-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4140 |
| _version_ | 1797856715229626368 |
|---|---|
| author | A. M. Chaulin D. V. Duplyakov |
| author_facet | A. M. Chaulin D. V. Duplyakov |
| author_sort | A. M. Chaulin |
| collection | DOAJ |
| description | Natriuretic peptides (NPs) are key diagnostic and prognostic biomarkers for patients with heart failure (HF). The main mechanism for increasing serum NP levels, which is characteristic of heart failure, is secretion in response to myocardial wall distention. At the same time, according to Russian and foreign literature, an increase in NPs is reported in a number of many other conditions that are not associated with HF. The study of these causes and mechanisms is necessary to improve the differential diagnosis of HF.This article discusses the mechanisms of increasing NPs and their diagnostic value in heart failure, as well as a number of other conditions, such as acute coronary syndrome and coronary artery disease, atrial fibrillation, exercise, kidney failure, taking cardiotoxic drugs (chemotherapy) and sacubitril/valsartan. The article also provides data on identifying NPs in non-invasively obtained biological fluids (urine and oral fluid). |
| first_indexed | 2024-04-09T20:45:02Z |
| format | Article |
| id | doaj.art-e0c7607765aa438b91f01421ed6deb56 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:45:02Z |
| publishDate | 2021-01-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-e0c7607765aa438b91f01421ed6deb562023-03-29T21:23:36Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-01-01254S10.15829/1560-4071-2020-41403085Increased natriuretic peptides not associated with heart failureA. M. Chaulin0D. V. Duplyakov1Samara Regional Clinical Cardiology Dispensary; Samara State Medical UniversitySamara Regional Clinical Cardiology Dispensary; Samara State Medical UniversityNatriuretic peptides (NPs) are key diagnostic and prognostic biomarkers for patients with heart failure (HF). The main mechanism for increasing serum NP levels, which is characteristic of heart failure, is secretion in response to myocardial wall distention. At the same time, according to Russian and foreign literature, an increase in NPs is reported in a number of many other conditions that are not associated with HF. The study of these causes and mechanisms is necessary to improve the differential diagnosis of HF.This article discusses the mechanisms of increasing NPs and their diagnostic value in heart failure, as well as a number of other conditions, such as acute coronary syndrome and coronary artery disease, atrial fibrillation, exercise, kidney failure, taking cardiotoxic drugs (chemotherapy) and sacubitril/valsartan. The article also provides data on identifying NPs in non-invasively obtained biological fluids (urine and oral fluid).https://russjcardiol.elpub.ru/jour/article/view/4140natriuretic peptidesheart failureexerciserenal failureatrial fibrillationsacubitril/valsartanfalse positive causes of elevation |
| spellingShingle | A. M. Chaulin D. V. Duplyakov Increased natriuretic peptides not associated with heart failure Российский кардиологический журнал natriuretic peptides heart failure exercise renal failure atrial fibrillation sacubitril/valsartan false positive causes of elevation |
| title | Increased natriuretic peptides not associated with heart failure |
| title_full | Increased natriuretic peptides not associated with heart failure |
| title_fullStr | Increased natriuretic peptides not associated with heart failure |
| title_full_unstemmed | Increased natriuretic peptides not associated with heart failure |
| title_short | Increased natriuretic peptides not associated with heart failure |
| title_sort | increased natriuretic peptides not associated with heart failure |
| topic | natriuretic peptides heart failure exercise renal failure atrial fibrillation sacubitril/valsartan false positive causes of elevation |
| url | https://russjcardiol.elpub.ru/jour/article/view/4140 |
| work_keys_str_mv | AT amchaulin increasednatriureticpeptidesnotassociatedwithheartfailure AT dvduplyakov increasednatriureticpeptidesnotassociatedwithheartfailure |