Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations

Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocu...

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Main Authors: Nariman Nassiri, Medi Eslani, Nekoo Panahi, Shiva Mehravaran, Alireza Ziaei, Ali R Djalilian
Format: Article
Language:English
Published: Knowledge E 2013-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2013;volume=8;issue=4;spage=351;epage=358;aulast=Nassiri
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author Nariman Nassiri
Medi Eslani
Nekoo Panahi
Shiva Mehravaran
Alireza Ziaei
Ali R Djalilian
author_facet Nariman Nassiri
Medi Eslani
Nekoo Panahi
Shiva Mehravaran
Alireza Ziaei
Ali R Djalilian
author_sort Nariman Nassiri
collection DOAJ
description Graft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD.
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spelling doaj.art-e0c898c61ccd4d8a92f5ea46f43fae592022-12-22T04:38:39ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2013-01-0184351358Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and RecommendationsNariman NassiriMedi EslaniNekoo PanahiShiva MehravaranAlireza ZiaeiAli R DjalilianGraft versus host disease (GVHD) is a common complication of allogeneic stem cell transplantation (allo-SCT). Ocular GVHD develops in approximately 40-60% of patients following allo-SCT and its most common clinical manifestations include keratoconjunctivitis sicca and cicatricial conjunctivitis. Ocular GVHD may lead to severe ocular surface disease, which can significantly diminish quality of life and restrict daily activities. It is thus important to monitor the condition closely since with timely diagnosis, irreversible damage can be avoided. The current review will focus on updated information regarding ocular GVHD.http://www.jovr.org/article.asp?issn=2008-322X;year=2013;volume=8;issue=4;spage=351;epage=358;aulast=NassiriAllogeneic Stem Cell Transplantation; Bone Marrow Transplantation; Ocular Graft Versus Host Disease; Dry Eye; Keratoconjunctivitis Sicca
spellingShingle Nariman Nassiri
Medi Eslani
Nekoo Panahi
Shiva Mehravaran
Alireza Ziaei
Ali R Djalilian
Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
Journal of Ophthalmic & Vision Research
Allogeneic Stem Cell Transplantation; Bone Marrow Transplantation; Ocular Graft Versus Host Disease; Dry Eye; Keratoconjunctivitis Sicca
title Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_full Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_fullStr Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_full_unstemmed Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_short Ocular Graft Versus Host Disease Following Allogeneic Stem Cell Transplantation: A Review of Current Knowledge and Recommendations
title_sort ocular graft versus host disease following allogeneic stem cell transplantation a review of current knowledge and recommendations
topic Allogeneic Stem Cell Transplantation; Bone Marrow Transplantation; Ocular Graft Versus Host Disease; Dry Eye; Keratoconjunctivitis Sicca
url http://www.jovr.org/article.asp?issn=2008-322X;year=2013;volume=8;issue=4;spage=351;epage=358;aulast=Nassiri
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AT medieslani oculargraftversushostdiseasefollowingallogeneicstemcelltransplantationareviewofcurrentknowledgeandrecommendations
AT nekoopanahi oculargraftversushostdiseasefollowingallogeneicstemcelltransplantationareviewofcurrentknowledgeandrecommendations
AT shivamehravaran oculargraftversushostdiseasefollowingallogeneicstemcelltransplantationareviewofcurrentknowledgeandrecommendations
AT alirezaziaei oculargraftversushostdiseasefollowingallogeneicstemcelltransplantationareviewofcurrentknowledgeandrecommendations
AT alirdjalilian oculargraftversushostdiseasefollowingallogeneicstemcelltransplantationareviewofcurrentknowledgeandrecommendations