3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery
3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Pharmaceutics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/13/11/1946 |
| _version_ | 1797508829026451456 |
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| author | Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck |
| author_facet | Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck |
| author_sort | Rafaela Santos de Oliveira |
| collection | DOAJ |
| description | 3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the use of 3D printing for the development of pharmaceutical and biomedical products for topical skin applications, covering plain dressing and products for the delivery of active ingredients to the skin. Based on the data acquired, the important growth in the number of publications over the last years confirms its interest. The semisolid extrusion technique has been the most reported one, probably because it allows the use of a broad range of polymers, creating the most diverse therapeutic approaches. 3D printing has been an excellent field for customizing dressings, according to individual needs. Studies discussed here imply the use of metals, nanoparticles, drugs, natural compounds and proteins and peptides for the treatment of wound healing, acne, pain relief, and anti-wrinkle, among others. The confluence of 3D printing and topical applications has undeniable advantages, and we would like to encourage the research groups to explore this field to improve the patient’s life quality, adherence and treatment efficacy. |
| first_indexed | 2024-03-10T05:09:25Z |
| format | Article |
| id | doaj.art-e0ccd2c756874d1fa72c4b8ac814aa8e |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-10T05:09:25Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-e0ccd2c756874d1fa72c4b8ac814aa8e2023-11-23T01:00:03ZengMDPI AGPharmaceutics1999-49232021-11-011311194610.3390/pharmaceutics131119463D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug DeliveryRafaela Santos de Oliveira0Stephani Silva Fantaus1Antonio José Guillot2Ana Melero3Ruy Carlos Ruver Beck4Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul. Avenida Ipiranga, 2752, Porto Alegre 90610-000, BrazilDepartamento de Produção e Controle de Medicamentos, Universidade Federal do Rio Grande do Sul. Avenida Ipiranga, 2752, Porto Alegre 90610-000, BrazilDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, School of Pharmacy, University of Valencia, Avenida Vicente Andres Estelles SN, 46100 Burjassot, SpainDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, School of Pharmacy, University of Valencia, Avenida Vicente Andres Estelles SN, 46100 Burjassot, SpainPrograma de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul. Avenida Ipiranga, 2752, Porto Alegre 90610-000, Brazil3D printing has been widely used for the personalization of therapies and on-demand production of complex pharmaceutical forms. Recently, 3D printing has been explored as a tool for the development of topical dosage forms and wound dressings. Thus, this review aims to present advances related to the use of 3D printing for the development of pharmaceutical and biomedical products for topical skin applications, covering plain dressing and products for the delivery of active ingredients to the skin. Based on the data acquired, the important growth in the number of publications over the last years confirms its interest. The semisolid extrusion technique has been the most reported one, probably because it allows the use of a broad range of polymers, creating the most diverse therapeutic approaches. 3D printing has been an excellent field for customizing dressings, according to individual needs. Studies discussed here imply the use of metals, nanoparticles, drugs, natural compounds and proteins and peptides for the treatment of wound healing, acne, pain relief, and anti-wrinkle, among others. The confluence of 3D printing and topical applications has undeniable advantages, and we would like to encourage the research groups to explore this field to improve the patient’s life quality, adherence and treatment efficacy.https://www.mdpi.com/1999-4923/13/11/1946additive manufacturingwound dressingFDMskin disordersfilmpatch |
| spellingShingle | Rafaela Santos de Oliveira Stephani Silva Fantaus Antonio José Guillot Ana Melero Ruy Carlos Ruver Beck 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery Pharmaceutics additive manufacturing wound dressing FDM skin disorders film patch |
| title | 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery |
| title_full | 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery |
| title_fullStr | 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery |
| title_full_unstemmed | 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery |
| title_short | 3D-Printed Products for Topical Skin Applications: From Personalized Dressings to Drug Delivery |
| title_sort | 3d printed products for topical skin applications from personalized dressings to drug delivery |
| topic | additive manufacturing wound dressing FDM skin disorders film patch |
| url | https://www.mdpi.com/1999-4923/13/11/1946 |
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