<i>Aspergillus fumigatus</i> Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis

<i>Aspergillus fumigatus</i> Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis

<i>Aspergillus fumigatus</i> is the most commonly isolated fungus in chronic lung diseases, with a prevalence of up to 60% in cystic fibrosis patients. Despite this, the impact of <i>A. fumigatus</i> colonisation on lung epithelia has not been thoroughly explored. We investig...

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Bibliographic Details
Main Authors: Katie Dunne, Emma Reece, Siobhán McClean, Sean Doyle, Thomas R. Rogers, Philip Murphy, Julie Renwick
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Journal of Fungi
Subjects:
<i>Aspergillus fumigatus</i>
inflammation
gliotoxin
supernatants
transepithelial electrical resistance
tight junctions
Online Access:https://www.mdpi.com/2309-608X/9/4/490

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