Perbandingan Pulihnya Syok pada Sindrom Syok Dengue Memakai Ringer Laktat dan Natrium Laktat Hipertonik
Standardized dengue shock syndrome (DSS) fluid resuscitation using isotonic crystalloid often cause fluid overload and reperfusion injury. The new innovation of fluid resuscitation in shock patients is using hypertonic sodium lactate. The study on fluid resuscitation using hypertonic sodium lactate...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Universitas Padjajaran
2013-09-01
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| Series: | Majalah Kedokteran Bandung |
| Subjects: | |
| Online Access: | http://journal.fk.unpad.ac.id/index.php/mkb/article/view/142 |
| Summary: | Standardized dengue shock syndrome (DSS) fluid resuscitation using isotonic crystalloid often cause fluid overload and reperfusion injury. The new innovation of fluid resuscitation in shock patients is using hypertonic sodium lactate. The study on fluid resuscitation using hypertonic sodium lactate in DSS children has never performed previously. This study aimed to find shock recovery difference between DSS children using hypertonic sodium lactate and Ringer lactate (RL). Study method was single blind randomized controlled trial. There were 62 children, 2–14 years met the inclusion criteria in pediatric division, Departement of Child Health Dr. Hasan Sadikin Hospital Bandung, June 2008–June 2010, four subjects were dropped out and 58 subjects were participated. Group I (30 subjects) received hypertonic sodium lactate and group II (28 subjects) received RL. The subjects were observed for capillary refill time and blood lactate as shock recovery predictor. Statistical analysis using t-test, Friedman test, and chi-square. The result showed fluid resuscitation using hypertonic sodium lactate was faster in shock recovery than RL (p<0.05). The significant difference of capillary refill time recovery start at 30 minutes, first, and second hour observation (p<0.05). The significant difference decrease in blood lactate showed at twelfth hour observation (p<0,05). This study concluded fluid resuscitation on DSS children using hypertonic sodium lactate has faster shock recovery compared to RL. |
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| ISSN: | 0126-074X 2338-6223 |