Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)s

Superior TRAIL gene expression and cancer cell apoptosis mediated by highly branched-linear poly(β-amino ester)s

Abstract Extensive efforts have been dedicated to enhancing the expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in cancer cells for the development of effective cancer treatments. However, highly safe and efficient delivery of TRAIL gene remains a significant challenge,...

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Bibliographic Details
Main Authors: Yitong Zhao, Tao Bo, Chenfei Wang, Dingjin Yao, Chaolan Pan, Weiyi Xu, Hao Zhou, Ming Li, Si Zhang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Nanobiotechnology
Subjects:
Cancer therapy
TRAIL gene
Branched-linear poly(β-amino ester)s
Cell apoptosis
Online Access:https://doi.org/10.1186/s12951-023-02169-7

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