Comparative dissolution studies on granules with acetaminophen and caffeine using the basket and paddle methods with simultaneous spectrophotometric determination of active substances

Comparative dissolution studies on granules with acetaminophen and caffeine using the basket and paddle methods with simultaneous spectrophotometric determination of active substances

Acetaminophen and caffeine, popular therapeutic substances used to relieve pain or alleviate the symptoms of cold. The aims of the study were the comparison of granules, in terms of dissolution rate and moreover the development of spectrophotometric method to the simultaneous determination of both a...

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Bibliographic Details
Main Authors: Szumilo Michal, Belniak Piotr, Kasperek-Nowakiewicz Regina, Holody Ewelina, Poleszak Ewa
Format: Article
Language:English
Published: Sciendo 2019-12-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
caffeine
acetaminophen
granules
basket apparatus
paddle apparatus
dissolution
Online Access:https://doi.org/10.2478/cipms-2019-0037

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